Table of Contents
- Quick Summary: Our Top 7 NMN Supplements
- Top 7 Best NMN Supplements
- How We Chose the Best NMN Supplements
- What is NAD?
- What is NMN?
- How NMN Supplements Work
- NMN Vs NR
- What are the Science-Backed Benefits of NMN Supplements?
- Are NMN Supplements Safe?
- What is the Optimal NMN Dosage?
- How to Choose the Best NMN Supplement
- FAQs
- Final Words
Nicotinamide mononucleotide (NMN) is one of 2025’s top anti-aging supplements, known for effectively boosting NAD+, a key molecule for energy and cellular health.
As NAD+ levels naturally drop with age, energy and mental clarity can decline.
To help you find the best NMN supplement, we tested and reviewed leading options using clinical studies, expert insights, and strict quality standards, simplifying your choice.
NMN + RESVERATROL
Cellular NAD+ booster with ultra-pure NMN and Resveratrol, at research-backed doses.*
Quick Summary: Our Top 7 NMN Supplements
To make your selection easier, here's a straightforward comparison of the best NMN supplements available in 2025:
Top 7 Best NMN Supplements
Here are some of the best NMN supplements to consider in 2025:
Omre NMN + Resveratrol – Best Overall for NAD+ Support
Nutricost NMN – Best Budget-Friendly NMN Supplement
Peak NMN – Best for Longevity Support
WonderFeel Youngr NMN – Best Premium Formula for Longevity
PartiQlar Pure NMN – Best Minimalist NMN Formula
Renue by Science LIPO NAD+ Complete – Best Comprehensive NAD+ Support
ProHealth NMN Pro™ 500 – Best High-Potency Option
1. Omre NMN + Resveratrol – Best Overall for NAD+ Support
Key Details:
Supply: 60 capsules (30 servings)
Ingredients: NMN, Resveratrol, BioPerine®
NMN Dose: 500 mg per serving
Pricing: $59.97 per month (discounts on subscriptions)
Refund Policy: 30-day money-back guarantee (includes shipping)
Omre NMN + Resveratrol tops our list for providing the best combination of ingredients to effectively raise NAD+ levels. It includes 500 mg of NMN, matched with an equal amount of Resveratrol, a potent antioxidant that helps maximize the anti-aging benefits.
According to a recent clinical study, Resveratrol works synergistically with NMN to boost mitochondrial health and cognitive performance (1). This supplement is especially good if you're seeking a complete NAD+ boosting package.
Its added BioPerine® enhances absorption, addressing the issue of NMN’s naturally low bioavailability. The capsule form is convenient and gentle on the stomach, making it easy to add to your daily routine.
Pricing is competitive for a premium NMN supplement, especially considering its high-quality ingredients and third-party testing. If you're new to NMN or want a trusted formula, Omre NMN + Resveratrol is an excellent choice.
Pros:
Effective NMN and Resveratrol combination
BioPerine® for improved absorption
Made in FDA-registered and GMP-certified facilities
Positive user feedback for energy and cognitive clarity
Cons:
Available exclusively online
Slightly pricier compared to simpler NMN products
2. Nutricost NMN – Best Budget-Friendly NMN Supplement
Key Details:
Supply: 60 capsules (30 servings)
Ingredients: NMN, Rice Extract, Hypromellose (Capsule)
NMN Dose: 500 mg per serving
Pricing: $33.95 one-time, $27.16 subscription
Refund Policy: 60-day money-back guarantee
Nutricost NMN is the best NMN supplement if you're on a tighter budget but still want a pure, high-quality option. Each capsule provides 500 mg of β-Nicotinamide Mononucleotide, precisely dosed and verified by third-party lab testing for purity and potency.
Nutricost keeps it simple, just NMN and minimal excipients like rice extract, making it ideal if you prefer straightforward supplements without unnecessary ingredients.
Users report noticing improvements in energy levels, and its vegetarian-friendly formula makes it accessible to almost everyone.
At just $27.16 per bottle with a subscription, Nutricost NMN is significantly more affordable than many competitors.
Pros:
Great value for money
Third-party tested for purity
Simple, vegetarian-friendly formula
Generous 60-day money-back guarantee
Cons:
Lacks added absorption enhancers
No complementary ingredients (e.g., Resveratrol)
3. Peak NMN – Best for Longevity Support
Key Details:
Supply: 90 capsules (30 servings)
Ingredients: NMN (375 mg), Berberine HCl, White Mulberry Extract, Spermidine, Lithium Orotate
NMN Dose: 375mg
Pricing: $100 per bottle (one-time), $85 with subscription
Refund Policy: 90 days
Peak NMN takes a more well-rounded approach by combining 375 mg of NMN with ingredients like Berberine, White Mulberry Extract, and Spermidine. These compounds support metabolic health, DNA repair, and inflammation control, key factors in aging well.
Instead of focusing only on NAD+ levels, this formula targets multiple aging pathways, including stress response and cellular resilience. It’s a smart option if you want broader support than a basic NMN supplement.
At $100 per bottle (or $85 with a subscription), it’s a premium pick, but the added benefits may be worth it for those seeking a more comprehensive longevity stack.
Pros:
Combines NMN with other longevity-supporting ingredients
Includes Berberine and Spermidine for metabolic and DNA repair benefits
Focuses on cellular health, inflammation, and energy
Designed for full-spectrum aging support
Cons:
Higher price point than standard NMN supplements
Refund policy not clearly stated on the product page
4. WonderFeel Youngr NMN – Best Premium Formula for Longevity
Key Details:
Supply: 60 capsules (30 servings)
Ingredients: NMN, Resveratrol, Hydroxytyrosol, Ergothioneine, Vitamin D3
NMN Dose: 900 mg per serving
Pricing: $88 one-time, $73 subscription
Refund Policy: 60-day money-back guarantee
WonderFeel Youngr NMN is a premium supplement formulated by longevity expert Dr. Andrew Salzman. Each serving delivers 900 mg of NMN along with powerful antioxidants like Resveratrol and Ergothioneine, aiming to boost NAD+ and cellular health.
Clinical studies support the formula's effectiveness. Dr. David Sinclair highlights that combining NMN with antioxidants can enhance overall benefits for cellular health and aging.
Priced higher at $73/month (subscription), it suits those looking for a comprehensive, science-backed NMN product focused on longevity.
Pros:
High-dose NMN (900 mg)
Antioxidant blend for enhanced results
Developed by longevity researchers
Strong customer satisfaction for energy and cognition
Cons:
Premium cost may not suit everyone
Best value through subscription only
5. PartiQlar Pure NMN – Best Minimalist NMN Formula
Key Details:
Supply: 60 capsules (30 servings)
Ingredients: Pure NMN powder, Vegetarian capsule
NMN Dose: 500 mg per serving
Pricing: $45 one-time, $39 subscription
Refund Policy: 30-day return policy
PartiQlar Pure NMN takes a minimalist approach, providing pure, high-quality NMN with no unnecessary fillers, additives, or extra ingredients. This straightforward formula appeals strongly if you prefer simplicity, transparency, and reliability in your supplements.
Each capsule contains precisely dosed NMN verified through independent third-party testing. Studies confirm that pure NMN at doses around 500 mg daily effectively supports mitochondrial health, energy levels, and cognitive function, making PartiQlar a trusted choice (3).
Affordably priced at $39 per bottle with a subscription, it's accessible and budget-friendly.
Pros:
Pure NMN with no fillers or unnecessary ingredients
Independent third-party purity testing
Affordable and excellent value
Positive feedback for noticeable energy improvements
Cons:
No complementary antioxidants or absorption enhancers
Packaging could improve for better NMN stability
6. Renue by Science LIPO NAD+ Complete – Best Comprehensive NAD+ Support
Key Details:
Supply: 90 capsules (30 servings)
Ingredients: NMN, NAD+, NR, Apigenin, Fisetin, Resveratrol
NMN Dose: 250 mg NMN (plus NAD+ and NR)
Pricing: $84.95 per bottle
Refund Policy: 30-day money-back guarantee
Renue by Science LIPO NAD+ Complete is unique, blending multiple NAD+ precursors (NMN, NR, NAD+) and beneficial antioxidants like Apigenin, Fisetin, and Resveratrol.
This comprehensive formula aims to provide robust NAD+ support from multiple angles, ensuring maximum effectiveness.
Clinical data supports combining different NAD+ precursors to maintain steady, high NAD+ levels throughout the day. Additionally, Fisetin and Apigenin are known for their anti-aging and anti-inflammatory benefits, further enhancing the supplement's longevity support.
Priced at $94.95 per month, it's an investment, but justified by its extensive ingredient list and science-backed combination. It's ideal if you’re committed to long-term NAD+ optimization and looking for a thorough, advanced formulation.
Pros:
Combines multiple NAD+ boosters for maximum effectiveness
Added antioxidants for broader anti-aging support
Strongly backed by longevity research
Positive user feedback for overall vitality improvements
Cons
Higher price compared to single-ingredient NMN products
Complex formulation may be overwhelming for beginners
7. ProHealth NMN Pro™ 500 – Best High-Potency Option
Key Details:
Supply: 30 capsules (30 servings)
Ingredients: NMN (pure β-Nicotinamide Mononucleotide), vegetarian capsule
NMN Dose: 500 mg per serving
Pricing: $39.90 per bottle
Refund Policy: 75-day money-back guarantee
ProHealth NMN Pro™ 500 offers a high-potency, pure NMN formula popular among experienced users seeking reliable NAD+ support.
ProHealth has an excellent reputation, maintaining rigorous quality control standards, and clearly showing third-party lab results for every batch.
Studies consistently demonstrate benefits of daily NMN supplementation at doses around 500 mg to 1,000 mg, including enhanced energy, cognitive clarity, and metabolic health. ProHealth’s NMN Pro delivers precisely this, ensuring consistent, measurable results.
At under $50, it balances high-potency and affordability perfectly, appealing if you want a dependable, daily NMN supplement without extra ingredients or complexity.
Pros:
Reliable high-potency NMN dose (500 mg)
Transparent third-party lab results
Excellent brand reputation and user trust
Long 75-day refund window
Cons
No additional antioxidants or absorption boosters
Simple formulation may not appeal to those seeking comprehensive supplements
How We Chose the Best NMN Supplements
To pick the top NMN supplements, we prioritized factors that directly impact quality, effectiveness, and value:
Purity & Quality: Third-party tested and GMP-certified for transparency and safety.
Optimal Dosage: Ideal dosages backed by clinical research (500–900 mg daily).
Absorption & Bioavailability: Evaluated forms like capsules, sublingual, and liposomal for maximum absorption.
Cost & Value: Compared affordability, price per serving, and overall value.
- Expert & Customer Reviews: Analyzed real-world experiences, expert endorsements, and verified testimonials.
What is NAD?
NAD (nicotinamide adenine dinucleotide) is a critical molecule that powers every cell in your body by converting nutrients into energy. Often called the "cellular energy currency," NAD supports essential processes like DNA repair, metabolism, and cellular health.
However, NAD levels naturally decline as you age, typically beginning in your late 20s to early 30s. Lower NAD levels can lead to fatigue, cognitive decline, slower metabolism, and other age-related issues.
Maintaining healthy NAD levels through supplementation can help keep your energy high and your body functioning optimally for longer.
What is NMN?
NMN (nicotinamide mononucleotide) is a supplement that helps raise NAD levels in your body. It’s naturally produced in small amounts and can also be found in some foods, but supplementation provides higher, more effective doses.
Your body converts NMN directly into NAD, helping maintain healthy cellular function, boosting energy, and supporting overall well-being.
Clinical studies show NMN supplements are safe and effective in raising NAD levels, improving metabolism, cognitive function, and energy production, especially as we age (4).
How NMN Supplements Work
NMN supplements help your body produce NAD+, a molecule essential for cellular energy, DNA repair, and overall vitality. NMN itself is a direct precursor, meaning it quickly converts into NAD+ within your cells, enhancing energy and cellular function.
"NMN supplementation has shown promising results in raising NAD+ levels effectively," notes Dr. David Sinclair, a leading longevity researcher from Harvard Medical School.
Clinical studies, including a 2021 trial from the University of Tokyo, found NMN boosted NAD+ levels significantly, improving metabolism and energy production in adults aged 40–60 (5).
By maintaining optimal NAD+ levels, NMN supplements support healthy aging by enhancing mitochondrial function, promoting DNA repair, and reducing inflammation.
Regular users often notice benefits such as increased daily energy, sharper cognitive function, better sleep, and healthier skin over time.
NMN Vs NR
NMN and NR (nicotinamide riboside) are both effective NAD precursors, but NMN directly converts into NAD, while NR first converts into NMN, then NAD. This makes NMN slightly more efficient for quickly boosting NAD levels.
What are the Science-Backed Benefits of NMN Supplements?
NMN supplements have been studied extensively for various potential health benefits. Here’s a clear, expert-backed breakdown:
Improved Energy and Reduced Fatigue
Many users quickly notice increased energy and less fatigue after starting NMN supplementation.
According to a 2021 study involving amateur runners, NMN doses between 600–1200 mg improved aerobic capacity and reduced fatigue by enhancing how muscles use oxygen during exercise (5).
Better Cognitive Function and Brain Health
NMN shows promise in supporting cognitive health and slowing age-related mental decline. Research by longevity expert Dr. David Sinclair has indicated NMN may improve blood flow to the brain and support memory and mental clarity by maintaining healthy NAD levels.
Enhanced Sleep Quality
NMN can help reset your body's internal clock, leading to better sleep. A 12-week study in 2022 showed older adults who supplemented with NMN reported better sleep quality and felt more energized during the day compared to placebo (6).
Stronger Metabolic Health and Easier Weight Management
Maintaining a healthy metabolism is harder with age. A clinical trial published in 2021 found NMN supplementation improved glucose metabolism and insulin sensitivity in overweight, prediabetic women (7).
This suggests NMN can support healthy weight management by improving how your body handles sugar and energy.
Healthier Skin and Hair
Your skin naturally loses its repair ability with age, leading to wrinkles and dryness. NMN supplements may boost collagen production and skin hydration by supporting NAD-dependent repair mechanisms (8).
Recent research also shows NMN can help reduce skin aging by minimizing compounds called AGEs, responsible for skin aging and wrinkles.
Muscle Strength and Better Physical Performance
NMN supplementation can help maintain muscle strength and improve recovery.
According to a 2022 research review, NMN improves mitochondrial function in muscles, which helps with endurance, strength, and faster recovery, important whether you're an athlete or an active older adult (9).
Heart Health and Cardiovascular Support
NMN supports heart health by maintaining vascular elasticity and lowering cardiovascular risks associated with aging.
Research indicates NMN activates protective enzymes called sirtuins, which help improve heart and arterial function, potentially reducing age-related cardiovascular issues (10).
NMN + RESVERATROL
Cellular NAD+ booster with ultra-pure NMN and Resveratrol, at research-backed doses.*
Hormonal Balance and Fertility Support
Preliminary animal studies suggest NMN can enhance fertility and protect egg health by improving NAD levels (11).
While human research is ongoing, these early findings show promise that NMN might help maintain hormonal balance and reproductive health as you age.
Support During Menopause
NMN supplements may reduce common menopausal symptoms like fatigue, hot flashes, and cognitive fog by restoring NAD levels.
Studies indicate that maintaining healthy NAD levels during menopause supports hormonal stability, bone density, and overall well-being, helping women feel more comfortable and energetic during this life stage (12).
DNA Repair and Longevity
NAD plays a vital role in DNA repair by activating PARP enzymes, which are essential in maintaining cellular health and preventing age-related damage.
According to longevity researchers, regular NMN supplementation supports efficient DNA repair processes, potentially extending healthspan by reducing cellular aging (13).
Improved Detoxification and Resilience to Toxins
Many detoxification processes rely on NAD-dependent enzymes.
A 2019 study demonstrated that higher NAD levels, achieved through NMN supplementation, enhance your body's ability to neutralize and eliminate environmental toxins, strengthening overall immune function and cellular resilience (14).
Are NMN Supplements Safe?
NMN supplements are generally safe when taken at recommended dosages (500–900 mg daily). Clinical studies report minimal side effects, usually limited to mild digestive discomfort or headaches.
Most research, including a notable 2022 clinical trial, found NMN safe even at higher doses (up to 2000 mg per day) with few side effects (15).
Common minor issues like nausea or mild headaches usually resolve quickly. Concerns around NMN and cancer growth remain speculative, with no human evidence supporting direct risks.
However, as NMN affects cellular activity, ongoing research is necessary.
Always consult your healthcare provider before starting NMN, especially if you have existing health concerns or take medication regularly.
What is the Optimal NMN Dosage?
The optimal daily dosage of NMN is between 500–900 mg, according to recent scientific research.
Most clinical studies, including a prominent 2021 trial led by Dr. Eric Verdin of the Buck Institute for Research on Aging, recommend around 900 mg daily for the best results (16).
Lower dosages (300–600 mg) can still offer benefits, but 900 mg appears most effective for noticeably increasing NAD+ levels, energy, and cellular health.
Although some research has tested higher doses (up to 2000 mg daily), no additional benefits have been consistently proven beyond the standard dosage range. It's best to stick with clinically validated amounts to maximize benefits safely.
How to Choose the Best NMN Supplement
Picking the right NMN supplement matters if you want safe, effective, and noticeable results. Consider these points before buying:
Purity and Quality: Choose supplements that have been independently tested for purity and potency. Look for certifications like NSF or GMP to ensure consistent quality.
Dosage: Pick products that provide 500–900 mg of NMN per serving. This is the dosage range most studies support for clear results.
Form and Absorption: Capsules are most common and convenient, but sublingual or liposomal NMN forms might offer faster absorption. However, capsules remain widely supported by clinical research.
Transparent Labeling: Avoid supplements with excessive fillers or unclear ingredient lists. Good brands disclose all ingredients clearly and transparently.
Value for Money: Calculate the price per dose to determine the overall value. Higher price doesn't always mean better quality. Look for affordable, high-purity options with solid user reviews.
- Expert and Customer Reviews: Trusted supplements typically have strong expert endorsements and plenty of genuine, positive user feedback.
FAQs
What time of day is best to take NMN?
NMN supplements are typically best taken in the morning, as they can boost energy and alertness. Avoid taking NMN late in the day to prevent sleep disturbances.
How quickly do NMN supplements start working?
Most users notice initial benefits, like increased energy and mental clarity, within 2–4 weeks. However, deeper benefits, including improved metabolic health and healthier skin, usually become noticeable after 2–3 months of consistent use.
Can NMN reverse aging?
NMN cannot reverse aging outright, but it supports healthy cellular functions and may help reduce signs of aging. By raising NAD+ levels, NMN supports energy, cognitive health, and overall vitality as you age.
Is liposomal NMN better?
Liposomal NMN may offer slightly improved absorption in theory, but current evidence supporting significant advantages over regular capsules is limited. Regular capsules remain well-supported by scientific research.
Are NMN supplements FDA-approved?
No dietary supplements, including NMN, are directly FDA-approved. However, NMN is considered safe under current regulations. Reputable brands follow strict manufacturing guidelines, such as GMP certification, for safety and quality assurance.
NMN vs. NR: Which is better for NAD+?
NMN directly converts into NAD+, making it slightly faster and more efficient than NR. Both effectively increase NAD+, but NMN generally has stronger evidence for quicker results, especially for energy and metabolism.
Final Words
NMN supplements offer a powerful way to boost NAD+ levels, supporting energy, mental clarity, and healthy aging.
When choosing an NMN supplement, consider purity, proper dosage, transparent labeling, and strong customer reviews.
Always consult a healthcare provider to ensure NMN supplements are right for your specific health needs.
If you're looking to maximize your NAD+ benefits, Omre NMN + Resveratrol combines two powerful ingredients for enhanced results; check availability today and start your journey to healthier aging.