I've tried a number of different types of "******** pills" and Afterdrink seems to be the only one that doesn't actually make me feel worse! Most of these supplements are crammed with B12 and a whole mess of random things that don't necessarily help you feel better in the AM.... fortunately, the combo of ingredients that Afterdrink uses makes sense on paper and in your body.
I should also note that I only take 2 (instead of the 3 recommended) pills beforehand, and only 2 (instead of 3) before bed. I'm 6' and 180 lbs and this seems to do me just fine.