Most people start with NAD injections 1 to 2 times per week for 4 to 6 weeks. After that, they switch to a maintenance schedule, usually once every 2 to 4 weeks, depending on their health goals and how they feel.

NAD injections are used to raise your body’s NAD+ levels, which help with energy, focus, aging, and recovery. 

This article breaks down how often you should get these shots, why the frequency matters, who benefits from them the most, and how to decide what’s right for you. 

You’ll also learn about a daily alternative to NAD injections that’s easier and more convenient for long-term health support.

NMN + RESVERATROL

Cellular NAD+ booster with ultra-pure NMN and Resveratrol, at research-backed doses.*

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How Often Should You Get NAD Injections?

Most people start with NAD injections 1–2 times a week for about a month, then taper down to once every few weeks. This helps build up NAD+ levels quickly and then keep them steady over time.

In the beginning, the goal is to restore what your body may have lost due to age, stress, or illness. This “loading phase” usually lasts 4 to 6 weeks. 

After that, you move into a “maintenance phase,” where the frequency depends on your energy needs and recovery goals. Some stick to once every 2–3 weeks, while others go monthly.

If you're using NAD+ for something more specific like athletic recovery, brain fog, or addiction support, your provider may recommend a more personalized schedule. 

The key is to monitor how your body responds and adjust as needed.

What Are NAD Injections?

how often should you get nad injectionsNAD injections deliver a dose of nicotinamide adenine dinucleotide (NAD+) directly into your body to help with energy, cellular repair, and brain function.

NAD+ is a coenzyme that your body needs to create energy and repair cells. As we age, NAD+ levels drop naturally, which can lead to fatigue, slower recovery, and brain fog. Injecting NAD+ helps bring those levels back up faster than relying on food or supplements alone.

These injections are typically given into the muscle or under the skin. They work more gradually than IV therapy but are more convenient, especially for people who want to keep up a routine without spending hours at a clinic.

Who Typically Uses NAD Injections?

NAD injections are popular among people looking for more energy, faster recovery, and mental clarity. They're also used in clinical settings for more specific support.

Here are some common groups that use NAD+ injections:

  • Busy professionals who need help managing fatigue, stress, or brain fog

  • Athletes and active individuals aiming to recover faster or improve performance

  • People over 35 looking to slow signs of aging and improve energy

  • Patients in addiction recovery using NAD+ to support detox and brain function

  • Individuals with chronic fatigue or burnout who need a stronger energy reset


Each person’s reason may be different, but the goal is the same, restoring energy and supporting better cellular health.

Recommended Frequency of NAD Injections

How often you should get NAD injections depends on whether you're starting fresh or maintaining your levels. Most people follow a three-phase approach: loading, maintenance, and, in some cases, intensive protocols.

1. Loading Phase (Initial Boost)

This is where most people begin. The goal here is to quickly raise your NAD+ levels and help your body reset. During this phase, NAD injections are usually given 1 to 2 times per week for 4 to 6 weeks.

This schedule helps replenish depleted stores and allows you to feel the benefits sooner. It’s often recommended for people experiencing fatigue, mental fog, or just starting their wellness journey. 

Many notice improved energy, better focus, and a general lift in how they feel during this phase.

2. Maintenance Phase

Once your NAD+ levels are up, you can reduce the frequency. Most people shift to one injection every 2 to 4 weeks, depending on how they feel and what they’re using it for.

This phase is about keeping your energy, brain function, and recovery on track. 

Some people with lower stress and healthier habits may only need a monthly shot, while others with demanding schedules or more wear and tear may benefit from biweekly support.

3. Intensive Protocols

In special cases, like during addiction recovery, burnout, or extreme athletic demands, more frequent injections may be needed.

Some providers recommend several injections per week over a short period to help with severe depletion. This is usually monitored closely by a medical professional. 

Once symptoms improve, most people move to a less frequent schedule.

Factors That Affect How Often You Should Get NAD Injections

Not everyone needs the same schedule. Your ideal injection frequency can vary based on several factors:

  • Age: NAD+ levels drop with age, especially after 40. Older adults often need more support to feel the full effects.

  • Stress levels: Chronic stress, poor sleep, or mental burnout can drain NAD+ faster and increase your need for regular shots.

  • Activity level: If you're very active, especially in endurance sports or intense training, you may need more frequent support to aid recovery.

  • Health conditions: People with fatigue syndromes, neurodegenerative conditions, or recovering from illness may require a more aggressive routine.

  • Goals: Are you aiming for general wellness, faster recovery, or managing a condition? Your reason for using NAD will shape your schedule.

NMN + RESVERATROL

Cellular NAD+ booster with ultra-pure NMN and Resveratrol, at research-backed doses.*

Shop NMN + RESVERATROL
Shop NMN + RESVERATROL

NAD Injections vs NAD IV Therapy

NAD Injections vs NAD IV TherapyBoth NAD injections and IV therapy aim to raise your NAD+ levels, but they differ in how they’re given, how fast they work, and how convenient they are.

Pros of NAD Injections:

  • Can be done at home or in short appointments

  • Less expensive than IV therapy

  • Good for long-term maintenance

  • Slower release offers more gradual effects

Cons of NAD Injections:

  • Smaller doses than IV, so effects may be less intense

  • May require more frequent sessions

  • Mild soreness at injection site is possible

Pros of NAD IV Therapy

  • High dose delivered directly into the bloodstream

  • Immediate results for energy, focus, and recovery

  • Often used in clinics for addiction recovery and anti-aging

  • Can include other nutrients in the IV mix

Cons of NAD IV Therapy

  • Takes 1 to 3 hours per session

  • Costs significantly more than injections

  • Less convenient, usually done in a clinic or with mobile providers

  • Some people experience stronger side effects if the drip is too fast

Are There Any Risks or Side Effects?

NAD injections are generally safe but can cause mild side effects in some people. The most common issues include soreness at the injection site, temporary fatigue, or nausea shortly after treatment.

These side effects are usually short-lived and go away on their own. In rare cases, people may feel flushed or dizzy during the first few sessions, especially if the dose is too high or injected too quickly.

To reduce the risk, injections are usually started with smaller doses and increased slowly. Always work with a trained provider who can monitor your response and adjust the schedule or dosage if needed.

How to Decide What’s Right for You

Choosing the right NAD+ injection schedule depends on your body, lifestyle, and goals. Here’s how to narrow it down:

  • Start with a health check: If possible, get baseline lab work or a provider consultation to assess your NAD+ needs.

  • Define your goal: Are you looking to boost energy, recover from stress, or support long-term aging? Your aim matters.

  • Track how you feel: After your first few shots, pay attention to changes in mood, energy, and focus.

  • Be flexible: You might need more at first and less later. Don’t be afraid to adjust your routine.

  • Consider convenience: If injections feel like too much, you might benefit from daily NAD+ precursors like NMN instead.

Looking for a Long-Term, Daily NAD+ Support Option?

If getting regular NAD injections or IV drips feels like a lot to manage, you’re not alone. Many people are now turning to daily NAD+ precursors for a simpler and more sustainable option.

It’s also worth noting that NAD+ IV therapy may not work the way it’s often marketed. Research shows that NAD+ molecules are too large to be effectively absorbed through IV drips, which limits their ability to truly boost energy, improve mental clarity, or slow aging (1).

Why NMN Might Be a Better Alternative:

  • Proven absorption: NMN (nicotinamide mononucleotide) converts directly into NAD+ inside cells, where it actually matters.

  • Daily convenience: Just one capsule a day, no needles, no clinic visits.

  • Long-term support: Helps maintain consistent NAD+ levels over time, not just quick bursts.

  • Backed by science: Animal and early human studies show NMN can support metabolism, energy, and healthy aging (23).

  • Cost-effective: More affordable than weekly injections or IV sessions.

Final Words

NAD injections can be a helpful tool for raising your energy, supporting recovery, and giving your brain a boost. 

Most people begin with weekly injections for a few weeks, then move to a personalized maintenance schedule. Your ideal routine depends on your health goals, age, and lifestyle.

But if you're looking for an easier, proven way to support NAD+ daily, NMN supplements are worth considering.

Want to try a trusted, science-backed NMN supplement? Omre’s NMN + Resveratrol formula is designed for better absorption and daily energy support.OMRE NMN + ResveratrolCheck availability and make it part of your long-term health plan.

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