The Complete Joe Rogan Supplement Guide (2025): What He Takes Daily

Joe Rogan’s Daily Supplement Stack at a Glance

Here’s a quick overview of the supplements Joe Rogan takes regularly. The table shows what each supplement does and when he typically takes it as part of his day.

Anti-Aging & Longevity

Joe Rogan takes NMN, NAD+, resveratrol, and exogenous ketones to support cellular repair, energy metabolism, and healthy aging. These supplements help him stay mentally sharp and physically active well into his 50s. 

They’re often discussed on his podcast, especially in episodes with longevity researchers like Dr. David Sinclair and Dr. Rhonda Patrick.

1. NMN & NAD

Joe uses both NMN supplements and NAD+ IV therapy to keep his energy and focus high. NMN (nicotinamide mononucleotide) is a compound that helps your body produce NAD+, which powers your cells and supports DNA repair. 

As NAD+ declines with age, cells lose efficiency, which can show up as fatigue, brain fog, or slower recovery.

One human study found that NMN improved muscle strength, mobility, and insulin sensitivity in older adults over a 12-week period (1). 

Rogan credits NAD+ therapy with helping him stay energized and recover faster from workouts and podcasting marathons.

He once described NAD+ drips as a “reboot” for his system.

2. Resveratrol

Resveratrol is a polyphenol found in grape skins and red wine. Joe takes it alongside NMN to support healthy aging. 

Resveratrol helps activate sirtuins, proteins linked to better metabolic function and reduced inflammation.

A study showed that resveratrol improved mitochondrial function and reduced markers of aging in middle-aged mice (2). In humans, it’s been linked to improved blood flow and heart health, especially in older adults.

Rogan often references the work of Dr. David Sinclair when talking about resveratrol. He’s said it helps him feel more resilient and focused.

3. Exogenous Ketones

Joe sometimes takes exogenous ketones to help with focus and endurance, especially when fasting or training in a low-carb state. 

These supplements increase ketone levels in the blood, which the brain and muscles can use for fuel instead of glucose.

A research found that ketone esters improved endurance performance in elite cyclists by increasing energy efficiency and delaying fatigue (3). 

Other studies suggest ketones may also help reduce oxidative stress and support metabolic health.

Rogan describes ketones as providing a “clean energy” that helps him stay sharp without the crash of sugar or caffeine.

Immunity & General Health Supplements

Joe Rogan takes a mix of vitamins, antioxidants, and targeted formulas to support his immune system, vision, and overall well-being. His daily stack includes high-dose vitamin D3, zinc, glutathione, and a specialized eye health supplement he credits for stabilizing his vision.

4. Vitamin D3 + K2

Vitamin D3 is a daily must-have for Joe, especially during the winter. He takes around 5,000 IU per day, often paired with vitamin K2. This combo helps direct calcium to the bones instead of arteries, which supports both heart and bone health.

Studies have shown that vitamin D3 reduces the risk of respiratory infections and boosts immune response (4). 

K2 has been linked to improved bone density and reduced arterial calcification (5).

Joe first started taking this combo after learning about it from Dr. Rhonda Patrick. “So many people are deficient in D3,” he said. “Especially if you’re inside all day.”

5. Zinc, Vitamin C, Glutathione

This trio forms the core of Rogan’s immune protocol, especially during travel or high-stress weeks. He often gets them through intravenous vitamin drips, but also uses oral forms.

• Zinc plays a major role in immune cell function. Studies show it can shorten the duration of colds and improve defense against infections (6).

• Vitamin C supports white blood cells and helps protect against oxidative damage. A Cochrane Review found that regular vitamin C supplementation slightly reduces cold duration and severity (7).

• Glutathione is considered the body’s master antioxidant. It helps detox cells and supports immune regulation. Low levels are linked to higher inflammation, and IV glutathione is often used to support recovery (8).

Joe says these supplements help him “bounce back” when he’s feeling worn out or run down.

6. Pure Encapsulations Macular Support

Rogan started using Macular Support from Pure Encapsulations after noticing some vision loss. The supplement includes lutein, zeaxanthin, and other antioxidants that help protect the retina and macula, the part of the eye responsible for sharp central vision.

A study found that these nutrients reduce the risk of progression in age-related macular degeneration. Other studies confirm they improve visual performance and filter harmful blue light.

“You know what stopped my vision loss dead in its tracks?” Rogan said. “Macular Support.” He continues to take it daily and credits it with keeping his eyesight stable.

Gut Health & Daily Greens

Joe Rogan supports his gut health with a mix of greens powders, nutrient-dense algae, and high-quality probiotics. 

These supplements help with digestion, nutrient absorption, and immune defense, especially important for someone with a physically demanding lifestyle and travel-heavy schedule.

Rogan has mentioned how much he values feeling “light, regular, and clear-headed,” which he credits in part to what he calls “daily gut support.” 

Here’s a look at the key supplements he uses to keep his digestive system running smoothly.

7. Athletic Greens (AG1)

Athletic Greens, now called AG1, is a foundational part of Rogan’s routine. He’s talked about using it every morning, especially while traveling. 

The powder contains 75+ ingredients, including whole-food sourced vitamins, minerals, digestive enzymes, prebiotics, probiotics, and adaptogens.

According to Rogan, “It’s my way of ensuring I get all the nutrients I need, especially when I’m on the go.” The blend includes spirulina, papaya, ashwagandha, and rhodiola, ingredients shown to support immunity, gut flora, and stress resilience.

One study found spirulina helps support healthy gut bacteria and may improve digestion and immune modulation (9). 

AG1 also contains Lactobacillus acidophilus and Bifidobacterium bifidum, two strains linked to reduced bloating and improved bowel regularity.

8. Onnit Earth Grown Nutrients & Spirulina/Chlorella

Joe doubles down on greens with Onnit Earth Grown Nutrients, another daily supplement loaded with organic vegetables, herbs, and fruits. He often combines it with separate spirulina and chlorella capsules for detox support and micronutrient density.

Spirulina and chlorella are algae that contain chlorophyll, protein, and antioxidants. Studies show they may help remove heavy metals and improve antioxidant status in the body (10). 

Rogan has mentioned these help him feel “cleaner and sharper,” especially after travel or cheat meals.

He’s a big believer in these greens not just for digestion, but for energy and recovery too.

9. Probiotics

Rogan often talks about gut health as the root of mental clarity and physical performance. He uses probiotic supplements like Seed’s Daily Synbiotic or Onnit’s Total Gut Health to help maintain a balanced microbiome.

Probiotics are live bacteria that support digestion, immune signaling, and nutrient breakdown. Different strains offer different benefits:

• Lactobacillus plantarum may reduce bloating and gas in people with IBS.

• Bifidobacterium lactis can help with constipation and regularity.

• Saccharomyces boulardii is a yeast strain that supports digestion and helps with antibiotic-related side effects.

Studies confirm that probiotics can help reduce inflammation in the gut, promote bowel regularity, and improve markers of immune function (11).

Joe's gut protocol reflects a “preventative maintenance” mindset, keep the gut healthy, and everything else works better.

NMN + RESVERATROL

Cellular NAD+ booster with ultra‑pure NMN and Resveratrol, at research‑backed doses.*

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Cognitive & Mood Support

Joe Rogan uses nootropics, adaptogens, and amino acids to stay focused, calm, and mentally sharp. Whether he’s hosting long-form podcasts, commentating for the UFC, or training, he relies on targeted brain support to stay in flow.

10. Alpha Brain Black Label

Alpha Brain Black Label is Rogan’s go-to cognitive enhancer. It’s a premium version of the original Alpha Brain formula, featuring higher doses and added compounds like citicoline and huperzine A.

Joe says it helps him stay “one step ahead” when he’s performing stand-up, doing UFC broadcasts, or recording podcast episodes. 

“Anytime cognitive function is important… I use Alpha Brain constantly,” he’s said.

Key ingredients include:

• Citicoline, which supports memory and mental speed

• Huperzine A, which helps maintain levels of acetylcholine, a neurotransmitter linked to learning and memory

• L-theanine and caffeine, for smooth, focused energy

11. New Mood, Theanine, Apigenin

For stress and sleep support, Rogan turns to Onnit’s New Mood, along with L-theanine and Apigenin. New Mood contains ingredients like 5-HTP and tryptophan, which help the body produce serotonin naturally. Rogan often takes it before bed or on recovery days.

L-theanine is an amino acid found in green tea. It promotes relaxation without causing drowsiness. One study found that combining L-theanine with magnesium helped reduce anxiety and sleep disturbances in adults (12).

Apigenin, found in chamomile, supports healthy sleep cycles. It has been shown to reduce cortisol and calm the nervous system (13).

Joe has said this combo helps him “shut down mentally” after high-stimulus days.

12. Neuro Gum

Neuro Gum is one of Joe’s quick fixes for focus. He’s said he “f***ing loves” chewing it before podcasting or workouts. Each piece contains caffeine, L-theanine, and B-vitamins, a combo designed to deliver fast-acting mental clarity.

Joe values how fast it works, calling it a great tool “when you need to lock in fast without the crash.”

Fitness, Recovery & Testosterone Support

Joe Rogan supports his strength, recovery, and hormone levels with a mix of creatine, testosterone therapy, muscle-supporting herbs, and advanced peptides. 

His approach combines time-tested basics with cutting-edge options that many of his expert guests have discussed on the podcast.

This stack helps him stay muscular, energized, and injury-resistant well into his 50s.

13. Creatine & Protein

Creatine and protein are at the foundation of Rogan’s fitness stack. He takes creatine gummies from Create, often six per day, and prefers hemp-based protein or Onnit Protein Bites for post-workout recovery.

Creatine is one of the most researched supplements for muscle strength and performance. A 2022 review found that daily creatine supplementation improves muscle mass, recovery, and exercise capacity across age groups (14).

Protein supports muscle repair and growth. Rogan favors hemp protein because it’s easy to digest and contains a complete amino acid profile. He’s also mentioned Onnit’s Protein Bites as a convenient and tasty alternative.

“Creatine is one of those things that I just trust. I feel stronger and I recover better,” Rogan has said.

14. Turkesterone, Tongkat Ali, Fadogia Agrestis

Joe adds these three plant-based compounds to support muscle growth and testosterone levels naturally. These supplements have gained popularity through podcast conversations with Dr. Andrew Huberman and others.

• Turkesterone is a type of ecdysteroid thought to improve protein synthesis. While human research is still early, some studies in animals suggest it can support lean muscle growth and reduce fatigue.

• Tongkat Ali (Eurycoma longifolia) may help increase free testosterone and improve mood and libido. A 2013 study found that men taking 200 mg daily showed improved hormone profiles and reduced stress (15).

• Fadogia Agrestis is a Nigerian shrub often combined with Tongkat Ali. It may support natural testosterone production, though clinical evidence in humans is limited.

Rogan uses these more cautiously, noting their potential, but also their need for more research.

15. TRT (Testosterone Replacement Therapy)

Joe Rogan has openly shared that he started testosterone replacement therapy (TRT) in his late 30s. He first used a cream, then later switched to injections.

TRT is prescribed when natural testosterone drops below healthy levels, often leading to fatigue, weight gain, and lower libido. 

Clinical trials have shown that TRT can improve muscle mass, bone density, and energy in men with low testosterone (16).

“I was like, ‘Oh my God, I feel so much better,’” Rogan said when describing how he felt after starting TRT.

He emphasizes the importance of getting blood work and working with a doctor before considering TRT.

16. BPC-157

BPC-157 is a peptide Rogan uses for recovery and healing. It’s short for Body Protection Compound-157, originally studied for healing gastric ulcers but now widely used off-label for tendon and muscle repair.

Animal studies show BPC-157 can speed up healing in tendons, muscles, and ligaments (17).

Human data is limited, but many biohackers and athletes, including Rogan, use it to bounce back from injury or intense training.

He’s mentioned that BPC-157 has helped him with joint issues and post-training soreness, especially as he’s gotten older.

Pre-Workout & Athletic Performance

Joe Rogan uses natural pre-workout supplements like Shroom Tech Sport and MCT oil to increase stamina, endurance, and mental clarity before exercise. 

He’s not a fan of jittery caffeine-heavy pre-workouts and instead chooses ingredients that support energy without the crash.

These products help him perform better in Jiu-Jitsu, lifting, and cardio without overstimulating the nervous system.

17. Shroom Tech Sport

Shroom Tech Sport by Onnit is one of Rogan’s favorite pre-workout formulas. It’s based on cordyceps mushrooms, which have been studied for their ability to improve oxygen use and delay fatigue. 

The blend also includes ashwagandha, green tea extract, and Rhodiola rosea, all known for supporting energy and endurance.

Rogan takes it before Jiu-Jitsu sessions or workouts that require lasting endurance. He’s said it gives him a noticeable boost without making him feel overstimulated.

18. MCT Oil

Medium-chain triglyceride (MCT) oil is a fast-absorbing fat that Joe often blends into his coffee. He uses Onnit’s Emulsified MCT Oil for its smoother texture and flavor. 

MCTs are converted into ketones, which provide a quick source of brain and body fuel, especially helpful during fasting or low-carb days.

Joe appreciates MCT oil for the “clean energy” it provides without the blood sugar spike of carbs. He often takes it in the morning to kickstart his day.

Expert Guests Who Helped Shape His Stack

Joe Rogan’s supplement choices are heavily influenced by expert guests like Dr. Rhonda Patrick and Dr. Andrew Huberman, who often share science-backed insights on nutrition, longevity, and brain health. These conversations have helped millions of listeners understand the “why” behind each supplement.

Many of Joe’s choices aren’t random; they’re based on what the experts recommend during long-form discussions on The Joe Rogan Experience. 

These guests bring years of research and practical tips that Joe applies to his own stack:

• Dr. Rhonda Patrick, a biomedical scientist, frequently talks about vitamin D, magnesium, sulforaphane, and aging-related pathways.

• Dr. David Sinclair, a longevity researcher from Harvard, has shaped Rogan’s use of NMN, NAD+, and resveratrol.

• Dr. Andrew Huberman, a neuroscientist from Stanford, has influenced Joe’s use of Tongkat Ali, nootropics, and sleep-focused compounds like apigenin.

• Aubrey Marcus, founder of Onnit, helped develop products like Alpha Brain and Shroom Tech Sport that are tailored to Rogan’s physical and mental demands.

• Dr. Mark Gordon, known for work in brain trauma and hormonal balance, has appeared to discuss testosterone and brain recovery protocols.

Should You Follow Joe Rogan’s Supplement Routine?

Not every supplement Joe Rogan takes will be right for you, but some of his top picks are backed by solid science and worth considering based on your goals. Whether you’re focused on energy, brain health, or aging, it’s about choosing what fits your body and lifestyle.

Start by defining what you actually need. Are you looking to improve focus? Recovery? Longevity? From there, choose supplements that match those goals. 

Rogan’s stack can seem overwhelming, but the truth is, even he built it over time with guidance from doctors and experts.

If you're curious where to begin, get bloodwork first. Knowing your vitamin D levels, testosterone, and inflammatory markers can help you avoid guesswork. 

From there, consider starting with the most research-backed supplements Joe uses. These include vitamin D3 + K2, creatine, omega-3s, magnesium, and NMN. 

NMN, in particular, stands out for its role in energy, repair, and aging support, especially when paired with resveratrol.

Conclusion

Joe Rogan’s supplement stack reflects more than just a wellness trend; it’s a snapshot of how performance, recovery, and longevity intersect in real life. 

From trusted basics like creatine and vitamin D to advanced options like NAD+ and BPC-157, Rogan’s routine is built around consistency, science, and learning from experts.

That doesn’t mean it’s one-size-fits-all. Use it as a reference, not a rulebook. 

Start with your health goals, get professional input, and build a stack that works for your needs, not someone else’s podcast schedule.If you’re exploring NMN and longevity support, try Omre NMN + Resveratrol. 

It’s a clean, well-formulated blend trusted by health-conscious users who want better energy, cellular repair, and real results backed by science.

Give your body what it needs to thrive, not just survive. Your next step starts with the right formula.

FAQs

What creatine does Joe Rogan use?

Joe Rogan takes Creatine Gummies from a brand called Create. He’s mentioned eating six gummies per day to support strength, recovery, and muscle energy.

Does Joe Rogan take AG1 daily?

Yes, Joe takes AG1 (formerly Athletic Greens) every day, especially while traveling. He likes it for its convenience and wide range of nutrients, including probiotics, greens, and adaptogens.

What NAD supplement does Rogan take?

Joe uses a combination of NMN capsules and NAD+ intravenous therapy. He takes NMN for daily use and uses IV NAD+ to support energy and cellular repair during recovery periods.

Does Joe Rogan take probiotics?

Yes, he includes probiotics like Seed’s Daily Synbiotic and Onnit Total Gut Health in his routine. He takes them to support digestion, immunity, and gut-brain function.

What nootropic does Rogan use?

Joe’s go-to nootropic is Alpha Brain Black Label by Onnit. He also uses Neuro Gum for quick focus and New Mood to support mood and relaxation.