Medically reviewed by Dr. Sara Alisha Khan, MD, PGDMLE

Omre Berberine is made for adults who want daily metabolic support from a clean, tested berberine supplement.

Each serving provides two forms of berberine:

• 600 mg Berberine HCL with 97% purity
• 400 mg Berberine Phytosome
• 2 vegan capsules per serving
• 30 servings per bottle

Berberine is a plant compound found in several plants, including barberry, goldenseal, goldthread, Oregon grape, phellodendron, and tree turmeric. In supplement form, it is widely studied for metabolic health, blood sugar metabolism, insulin sensitivity, lipid metabolism, AMPK activity, and cellular energy pathways.

Omre uses a dual-action formula because not all berberine supplements are built the same. Berberine HCL is a common, well-known form. Berberine Phytosome is a phospholipid-based form designed to support better absorption.

This product is not a medicine and does not treat, cure, or prevent disease. It is a daily supplement for adults who want a clear, tested berberine formula that is easy to compare.

Quick Buy Facts

Omre Berberine is made for adults comparing berberine supplements by dose, form, testing, and value.

• Price: $49.00 per bottle
• Serving size: 2 vegan capsules
• Servings per bottle: 30
• Cost per serving: $1.63
• Berberine HCL: 600 mg with 97% purity
• Berberine Phytosome: 400 mg
• Third-party tested for dose, purity, bacteria, fungus, and heavy metals
• Made in the USA in GMP-certified facilities
• 30-day money-back guarantee
• Free US shipping on orders over $80

Buying directly from Omre.co helps you receive the official formula, current pricing, verified testing standards, and Omre’s refund policy.

Why People Choose Omre Berberine

Omre Berberine is made for people who want a clear berberine supplement with listed ingredient forms, stated purity, and third-party testing details.

Each serving gives you:

• 600 mg Berberine HCL with 97% purity
• 400 mg Berberine Phytosome
• Two forms of berberine in one formula
• 30 servings per bottle
• Vegan capsules
• Third-party lab testing
• Testing for dose, purity, bacteria, fungus, and heavy metals
• Made in the USA
• Made in GMP-certified facilities
• Doctor-developed formula
• 30-day money-back guarantee
• Free US shipping on orders over $80

Many berberine supplements use only standard Berberine HCL. Others do not clearly list purity, testing standards, or batch quality details.

Omre takes a more complete route by combining Berberine HCL with Berberine Phytosome, giving shoppers a formula built around dose, absorption support, and transparency.

It is a strong fit for people comparing berberine supplements by form, serving size, purity, testing, manufacturing standards, and value.

What This Berberine Supplement Supports

Omre Berberine is designed to support:

• Healthy blood sugar metabolism
• Insulin sensitivity
• Metabolic health
• AMPK activity
• Cellular energy pathways
• Healthy cholesterol levels already within the normal range
• Lipid metabolism
• Fewer energy crashes
• Craving control support
• Long-term metabolic wellness
• Weight management support when paired with healthy habits

Berberine does not work like a quick stimulant. Think of it more like daily support for the body’s metabolic “control room.”

One key area of interest is AMPK. AMPK acts like an internal energy sensor inside the body. It helps cells respond to energy needs and plays a role in glucose metabolism, fat metabolism, and cellular energy balance.

Research has studied berberine for several metabolic markers, including blood glucose, HbA1c, insulin resistance, triglycerides, total cholesterol, and LDL cholesterol (1, 2).

That does not mean berberine replaces medication, diet, exercise, sleep, or medical care. It means berberine has become one of the most studied plant compounds in the metabolic health supplement category.

Doctor-Developed Metabolic Support

“As a gastroenterologist, I focus on how nutrients are absorbed and the purity of what people consume. Omre’s commitment to bioavailable, clean ingredients reflects what I believe supplements should prioritise.”

Dr. Sung Jae Hwang
Medical Doctor, MD
Gastroenterologist

Product Specifications

Product Name: Omre Berberine

Product Type: Berberine supplement

Main Category: Metabolic health and healthy aging supplement

Serving Information:

• Serving Size: 2 vegan capsules
• Servings per Bottle: 30 servings

Active Ingredients per Serving:

• Berberine HCL 97% purity: 600 mg
• Berberine Phytosome: 400 mg

Berberine Source:

• Berberine HCL from Indian Barberry extract root, Berberis aristata
• Berberine Phytosome from Berberis aristata extract root and phospholipid complex from pea, sunflower, and grape seed

Other Ingredients:

• Vegetable cellulose capsule
• Nu-FLOW rice concentrate

Suggested Use:

Take 2 capsules daily with food, or as directed by your healthcare provider.

Quality & Testing:

• Third-party lab tested
• Tested for dose, purity, bacteria, fungus, and heavy metals
• Made in the USA
• Made in GMP-certified facilities
• 30-day money-back guarantee
• Free US shipping on orders over $80

Storage: Store in a cool, dry place.

Price and Serving Value

Omre Berberine is priced at $49.00 per bottle. Each bottle provides 30 servings.

That breaks down to:

• $1.63 per serving
• About $0.82 per capsule
• 600 mg Berberine HCL per serving
• 400 mg Berberine Phytosome per serving

Subscription pricing is also available at $46.55 per bottle for a 1-month supply, based on the current Subscribe & Save option.

You can also choose:

• 1-month supply with 5% off
• 3-month supply with 10% off
• 6-month supply with 20% off

Price matters, but a berberine supplement should not be judged by price alone.

A better comparison looks at:

• Berberine form
• Berberine dose
• Purity
• Bioavailability support
• Serving size
• Third-party testing
• Manufacturing standards
• Refund policy

A cheaper berberine capsule may look good at first. But if it uses only generic berberine, gives no purity details, and does not publish testing standards, the real value may be harder to judge.

How to Take Omre Berberine

Take 2 capsules daily with food, or follow the advice of your healthcare provider.

Simple routine:

• Take 2 capsules daily
• Take with a meal
• Use consistently
• Store in a cool, dry place
• Speak with your healthcare professional if you take medication or manage a medical condition

Taking berberine with food may also be easier on the stomach. Some people experience digestive discomfort with berberine, including nausea, constipation, diarrhea, or stomach upset (4).

Metabolic health supplements work best when the rest of the routine makes sense too. Food quality, protein intake, movement, sleep, stress, and consistent meal timing still do a lot of the heavy lifting.

Why Omre Uses Berberine HCL and Berberine Phytosome

Omre uses two forms of berberine because each one plays a different role in the formula.

Berberine HCL is one of the most common forms used in berberine supplements. It is widely used because it is stable, familiar, and easy to compare across products.

Berberine Phytosome is different. It combines berberine with phospholipids, which are fat-like compounds used to support absorption. A human pharmacokinetic study found that Berberine Phytosome improved berberine absorption compared with unformulated berberine (3).

That matters because berberine is known for having low oral bioavailability. In plain English, standard berberine may not absorb as well as shoppers expect.

Omre combines:

• 600 mg Berberine HCL with 97% purity
• 400 mg Berberine Phytosome

This gives the formula a dose-plus-absorption-support angle, instead of relying on only one form.

What Is AMPK and Why Does It Matter?

AMPK stands for adenosine monophosphate-activated protein kinase.

That name is a mouthful, so here is the simple version: AMPK helps cells sense and manage energy.

When AMPK activity is supported, it is linked with several metabolic processes, including:

• Glucose uptake
• Fat metabolism
• Cellular energy balance
• Mitochondrial function
• Insulin sensitivity pathways
• Metabolic flexibility

Berberine is commonly discussed as a natural AMPK activator. This is one reason it has become popular in healthy aging and metabolic health formulas (2).

As people age, metabolic flexibility can change. Some people notice more energy swings, more cravings, changes in weight management, or less steady blood sugar response after meals.

A berberine supplement is not a magic switch. But it may support some of the same metabolic pathways that matter for long-term energy balance and healthy aging.

Berberine for Blood Sugar and Insulin Sensitivity Support

Berberine is widely studied for blood sugar metabolism and insulin sensitivity.

Clinical research has looked at berberine in people with type 2 diabetes and other metabolic concerns. A systematic review and meta-analysis reported that berberine was associated with improvements in several metabolic markers, including fasting blood glucose, HbA1c, insulin resistance, and lipid markers (1).

For a supplement page, the careful wording matters.

Omre Berberine is designed to support:

• Healthy blood sugar metabolism
• Insulin sensitivity
• Fewer energy crashes
• Steadier daily metabolic support

It is not intended to treat diabetes, replace prescribed medication, or manage a diagnosed medical condition.

If you take insulin, metformin, GLP-1 medication, sulfonylureas, or any blood sugar-lowering medication, speak with your healthcare professional before using berberine.

Berberine and Cholesterol Support

Berberine is also studied for lipid metabolism.

Some clinical research has looked at markers such as:

• Total cholesterol
• LDL cholesterol
• HDL cholesterol
• Triglycerides
• ApoB-related pathways
• Liver-related metabolic markers

A review on berberine and metabolic syndrome describes several possible metabolic actions, including effects linked with glucose and lipid metabolism (2).

Omre Berberine is designed to support healthy cholesterol levels already within the normal range. It should not be used as a replacement for cholesterol medication or medical care.

If you take statins, blood pressure medication, blood thinners, or medication for heart health, talk with your healthcare professional before starting berberine.

Berberine and Gut Microbiome Support

Berberine is also studied for its relationship with gut health and the gut microbiome.

The gut microbiome is the community of bacteria and other microbes that live in the digestive tract. These microbes are connected with digestion, immune signaling, metabolism, and how the body responds to nutrients.

Research on berberine has looked at how it may influence gut bacteria and metabolic pathways connected with glucose and lipid metabolism (2). This does not mean berberine is a probiotic or a treatment for gut conditions.

A more careful way to say it is that berberine may support metabolic health partly through pathways connected with the gut microbiome.

Omre Berberine is mainly positioned as a metabolic health supplement, but gut-related mechanisms help explain why berberine appears in both metabolic health and digestive wellness discussions.

Berberine HCL vs Berberine Phytosome

Berberine HCL and Berberine Phytosome are both forms of berberine, but they are not the same.

Berberine HCL is a standard form used in many berberine capsules. It is common, easy to compare, and widely used in supplements.

Berberine Phytosome is a phospholipid-based form designed to support absorption. In a human study, Berberine Phytosome showed improved absorption compared with unformulated berberine (3).

Here is the simple comparison:

Berberine HCL

• Common form of berberine
• Easy to compare across supplements
• Used in many research and supplement formulas
• Omre uses 600 mg per serving
• Omre lists 97% purity

Berberine Phytosome

• Phospholipid-based berberine form
• Designed to support better absorption
• Uses a complex from pea, sunflower, and grape seed phospholipids
• Omre uses 400 mg per serving
• Adds a bioavailability-support angle to the formula

Omre includes both forms in one daily berberine supplement.

Berberine Capsules vs Berberine Tablets

People searching for berberine capsules, berberine tablets, or berberine pills are mostly looking for an easy way to take berberine daily.

Omre Berberine comes in vegan capsule form. Capsules are a common choice for berberine supplements because they can hold powdered extracts and specialized ingredient forms without the same compression process used for tablets.

Still, capsule vs tablet is not the biggest question.

When comparing berberine capsules or tablets, check:

• How much berberine is in each serving?
• What form of berberine is used?
• Is it Berberine HCL, Berberine Phytosome, or another form?
• Is the purity listed?
• Is the serving size clear?
• Is it third-party tested?
• Are heavy metals and microbes tested?
• Is it made in a GMP-certified facility?
• Are safety warnings easy to find?
• Does the brand publish quality details?

A strong berberine supplement should be easy to understand before you buy it.

Berberine Supplement Comparison

Berberine Form

• What to check: Does the formula use Berberine HCL, Berberine Phytosome, or another form?
• Omre Berberine: 600 mg Berberine HCL + 400 mg Berberine Phytosome

Purity

• What to check: Is the Berberine HCL purity listed?
• Omre Berberine: 97% purity

Absorption Support

• What to check: Does the product use a bioavailability-focused form?
• Omre Berberine: Includes Berberine Phytosome

Serving Size

• What to check: Is the daily serving easy to understand?
• Omre Berberine: 2 vegan capsules

Servings

• What to check: How many servings are in one bottle?
• Omre Berberine: 30 servings

Price Per Serving

• What to check: Is the cost clear?
• Omre Berberine: $1.63 per serving, based on $49.00 bottle price

Testing

• What to check: Is it third-party tested?
• Omre Berberine: Tested for dose, purity, bacteria, fungus, and heavy metals

Manufacturing

• What to check: Where is it made?
• Omre Berberine: Made in the USA in GMP-certified facilities

Refund Policy

• What to check: Is there a guarantee?
• Omre Berberine: 30-day money-back guarantee

Omre Berberine vs Generic Berberine Supplements

Many berberine supplements look similar online. The details tell a different story.

Some products use only standard Berberine HCL. Some do not list purity. Some do not explain testing. Some give a big number on the front label but make the serving size hard to compare.

Omre Berberine uses:

• 600 mg Berberine HCL with 97% purity
• 400 mg Berberine Phytosome
• Vegan capsules
• Third-party lab testing
• Testing for dose, purity, bacteria, fungus, and heavy metals
• Made in the USA
• Made in GMP-certified facilities

The formula is built for metabolic health, blood sugar metabolism, insulin sensitivity, AMPK support, cellular energy, and healthy aging.

It is a dual-form berberine formula that combines standard Berberine HCL with Berberine Phytosome for absorption support. It is a dual-form berberine formula with clearer quality and testing details.

Why Omre Is Worth Comparing With Top Berberine Supplements

Omre Berberine is worth comparing with other top berberine supplements because it covers the main details careful shoppers look for: form, dose, purity, absorption support, testing, and manufacturing quality.

The formula uses two forms of berberine per serving:

• 600 mg Berberine HCL with 97% purity
• 400 mg Berberine Phytosome

That gives shoppers clear active ingredient amounts without relying on a hidden proprietary blend.

Omre is also third-party tested for dose, purity, bacteria, fungus, and heavy metals.

The point is not to claim Omre is the number one berberine supplement. The better point is simpler: the formula is clear, tested, and built around ingredients that fit the metabolic health and healthy aging category.

What to Expect With Omre Berberine

Berberine is not a stimulant, and results can vary from person to person.

The product is designed for daily metabolic support over time, not overnight change.

Some people may use berberine for:

• Blood sugar stability support
• Fewer energy crashes
• Craving control support
• Steadier daily energy
• Metabolic efficiency
• Long-term metabolic wellness
• Weight management support when paired with healthy habits

A simple way to think about it:

• From 30 days: Some people may look for steadier energy and fewer post-meal crashes.
• From 90 days: Some people may look for better consistency with cravings, energy, and daily metabolic routine.
• From 6 to 12 months: People focused on long-term health may use berberine as part of a broader plan that includes food quality, movement, sleep, and regular health checkups.

Supplements work best when they are part of a routine you can stick with.

Third-Party Testing and Quality

Omre Berberine is third-party tested every batch.

Testing checks:

• Berberine HCL content
• Ingredient purity
• Heavy metals
• Bacteria
• Fungus
• Microbial safety

Omre’s quality promise is built around clear formulas, published testing, GMP manufacturing, and made-in-USA production.

Important Safety Information

Omre Berberine is made for adults. Do not use this product if you are pregnant, nursing, under 18, or giving supplements to an infant or child.

Speak with your healthcare professional before use if you take prescription medication, have a medical condition, or are planning a medical procedure.

This is very important if you take:

• Blood sugar medication
• Insulin
• Metformin
• GLP-1 medication
• Blood pressure medication
• Cholesterol medication
• Blood thinners
• Heart medication
• Antibiotics
• Immune-related medication
• Long-term prescription medication

Berberine may interact with medications. It may also cause digestive side effects in some people, including stomach discomfort, constipation, diarrhea, nausea, or vomiting (4).

Stop use and contact a healthcare professional if you notice an unwanted reaction.

Keep out of reach of children. Store in a cool, dry place.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What Customers Are Saying

Omre Berberine is rated 5.0 out of 5 stars based on 2 customer reviews.

Review themes include:

• Customers choosing Omre because they trust the brand’s product quality
• Buyers liking that Omre products are natural and made without unnecessary fillers
• One customer using Omre Berberine alongside Omre NMN + Resveratrol
• One customer noting that they are giving the product more time, since berberine may take consistent use

From Omre

Why We Started Omre

Omre was founded by Dr. Pedram Kordrostami with a clear goal: make supplements that use thoughtful formulas, research-backed doses, and ingredients that fit real health routines.

The supplement shelf can be noisy. Some products chase trends. Some hide weak doses inside long blends. Omre takes a cleaner path by focusing on ingredient quality, testing, and clear formulas.

Our Formulation Philosophy

Omre Berberine was built around two core choices.

First, the formula uses 600 mg Berberine HCL with 97% purity.

Second, it includes 400 mg Berberine Phytosome, a phospholipid-based form designed to support absorption.

The goal is not to make a loud label. The goal is to make a daily berberine supplement that is easy to understand, easy to compare, and built for metabolic health support.

Our Quality Promise

Every bottle is made in the USA in GMP-certified facilities. The formula is third-party tested for dose, purity, bacteria, fungus, and heavy metals.

Omre gives shoppers the details they need before buying: active ingredient amounts, serving size, ingredient forms, testing standards, and manufacturing quality.

The Omre Difference

Omre does not use a hidden proprietary blend in this formula. Each key ingredient amount is listed clearly.

That matters because two berberine supplements can look similar at first glance but offer very different forms, doses, purity levels, and testing standards.

How to Choose a Berberine Supplement

Berberine supplements can look similar online. One bottle may say berberine 500 mg. Another may say Berberine HCL, Berberine Phytosome, berberine complex, Indian barberry extract, or Berberis aristata root extract.

Before buying, check:

• What form of berberine does it use?
• How much berberine is in each serving?
• Is the purity listed?
• Is the serving size clear?
• Does it use Berberine HCL, Berberine Phytosome, or both?
• Is it third-party tested?
• Does testing include heavy metals and microbes?
• Is it made in a GMP-certified facility?
• Are the directions clear?
• Are safety warnings easy to find?
• Is there a refund policy?
• Does the brand explain what makes the formula different?

A higher number on the label does not automatically mean a better product. Form, purity, absorption support, testing, and transparency all matter.

Omre Berberine was made for people who want a clear daily formula with 600 mg Berberine HCL, 400 mg Berberine Phytosome, third-party testing, and clear serving details.

Frequently Asked Questions

What is the best berberine supplement?

The best berberine supplement depends on the form, dose, purity, testing standards, ingredient transparency, and your health goals. Omre Berberine uses 600 mg Berberine HCL with 97% purity plus 400 mg Berberine Phytosome in one daily formula.

What is berberine?

Berberine is a yellow plant compound found in plants such as barberry, goldenseal, goldthread, Oregon grape, phellodendron, and tree turmeric. In supplement form, it is commonly used for metabolic health, blood sugar metabolism, insulin sensitivity, AMPK support, and lipid metabolism.

What is Berberine HCL?

Berberine HCL is a common form of berberine used in supplements. Omre uses 600 mg Berberine HCL per serving, with 97% purity.

What is Berberine Phytosome?

Berberine Phytosome is a phospholipid-based form of berberine designed to support better absorption. Omre includes 400 mg Berberine Phytosome per serving.

Why does Omre use two forms of berberine?

Omre combines Berberine HCL and Berberine Phytosome to support both dose and absorption. Berberine HCL is a widely used form. Berberine Phytosome adds a bioavailability-support angle to the formula.

Is Omre Berberine a 1000 mg berberine supplement?

Each serving provides 600 mg Berberine HCL plus 400 mg Berberine Phytosome. Since Berberine Phytosome is a phospholipid complex, it is better to compare the two listed forms separately instead of treating the full 1,000 mg as plain Berberine HCL.

What is berberine used for?

Berberine supplements are commonly used to support metabolic health, healthy blood sugar metabolism, insulin sensitivity, lipid metabolism, AMPK activity, cellular energy, and weight management when paired with healthy habits.

Does berberine support blood sugar?

Berberine has been studied for blood glucose and insulin-related markers. Omre Berberine is designed to support healthy blood sugar metabolism. It is not intended to treat diabetes or replace medication.

Does berberine support insulin sensitivity?

Berberine is studied for insulin sensitivity and insulin resistance-related markers. Omre Berberine is designed to support insulin sensitivity as part of a healthy routine.

Does berberine support cholesterol?

Berberine has been studied for lipid markers such as triglycerides, total cholesterol, and LDL cholesterol. Omre Berberine is designed to support healthy cholesterol levels already within the normal range.

What is AMPK?

AMPK is an enzyme that helps cells sense and manage energy. It is involved in glucose metabolism, fat metabolism, and cellular energy balance. Berberine is commonly discussed as a natural AMPK activator.

How long does berberine take to work?

Results can vary. Some people may look for changes in energy stability, cravings, or post-meal crashes after consistent use. Others may not notice clear short-term effects. Metabolic health depends on diet, movement, sleep, age, baseline health, and medication use.

Can I take berberine with metformin?

Do not combine berberine with metformin or other blood sugar medication unless your healthcare professional says it is appropriate. Berberine may affect blood sugar and may interact with medication.

Can I take berberine with blood pressure medication?

Talk with your healthcare professional before taking berberine if you use blood pressure medication. Berberine may interact with medications and may not be suitable for everyone.

Where can I buy a berberine supplement online?

You can buy Omre Berberine directly from Omre.co. Each serving provides 600 mg Berberine HCL with 97% purity plus 400 mg Berberine Phytosome.

Often Paired With

Customers interested in Berberine may also compare it with other Omre formulas for healthy aging, cellular wellness, and metabolic support.

• NMN + Resveratrol: NAD+ support, cellular energy, recovery, and healthy aging support
• Glycine + NAC: Glutathione balance and antioxidant defense
• TMG + B-Complex: Methylation support and B-vitamin support
• Urolithin A: Mitochondrial and muscle health support
• Spermidine: Cellular renewal and autophagy support

Final Buying Note

Omre Berberine is a strong berberine supplement to compare if you want a capsule-based formula with Berberine HCL, Berberine Phytosome, third-party testing, and clear ingredient amounts.

It may be a good fit for adults looking for daily support for metabolic health, blood sugar metabolism, insulin sensitivity, AMPK activity, lipid metabolism, cellular energy, and healthy aging.

It is not a medicine. It should not be used to diagnose, treat, cure, or prevent disease.

For the best comparison, look beyond the front label. Check the berberine form, dose, purity, absorption support, testing, manufacturing standards, safety warnings, customer reviews, and refund policy.

References

1. Guo J, et al. The Effect of Berberine on Metabolic Profiles in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Oxidative Medicine and Cellular Longevity. 2021.
2. Och A, et al. Berberine, a Herbal Metabolite in the Metabolic Syndrome. Molecules. 2022.
3. Petrangolini G, et al. Development of an Innovative Berberine Food-Grade Formulation with an Ameliorated Absorption: In Vitro Evidence Confirmed by Healthy Human Volunteers. 2021.
4. National Center for Complementary and Integrative Health. In the News: Berberine. Last updated June 2023.