What Is the Best Quercetin Supplement? Start With Absorption, Not Milligrams
Updated on Jul 25, 2026
Table of contents
- What Is Quercetin?
- Why Take a Quercetin Supplement if Quercetin Is Found in Food?
- The Problem With Plain Quercetin
- What Does Bioavailability Mean?
- Quercetin With Bromelain: What Does the Pairing Mean?
- What Is Quercetin Phytosome?
- What Did the Human Absorption Study Find?
- Does Higher Absorption Mean Better Results?
- Why We Pair Quercetin With Fisetin
- What Is Inside Omre Quercetin + Fisetin?
- Why We Keep the Formula Focused
- Third-Party Testing Changes the Question
- What a High-Quality Quercetin Supplement Should Show
- Who May Prefer Quercetin With Bromelain?
- Who May Prefer Omre Quercetin + Fisetin?
- Do Not Choose Quercetin by Milligrams Alone
- Frequently Asked Questions
- References
Quercetin supplements can look remarkably similar.
One bottle provides 500 mg. Another provides 1,000 mg. Some add bromelain. Others add vitamin C, zinc, or a long list of plant extracts.
It is tempting to choose the biggest number and move on.
That misses the most important part.
Quercetin has a known absorption challenge. A large serving of plain powder may look impressive on the label, but milligrams alone do not tell you how the formula behaves after you swallow it.
The best quercetin supplement should answer a better set of questions:
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What form of quercetin does it use?
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Has that form been studied in people?
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What else is included?
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Are all amounts clearly disclosed?
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Has the finished product been independently tested?
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Can the routine fit into your day?
Those details matter more than a large number on the front.
What Is Quercetin?
Quercetin is a flavonoid, a natural plant compound found in many fruits, vegetables, and drinks.
Common food sources include:
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Red and yellow onions
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Apples
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Capers
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Berries
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Cherries
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Kale
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Tea
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Grapes
Plants produce flavonoids partly in response to sunlight and environmental stress.
Inside the human body, researchers have studied quercetin for antioxidant activity, cellular signaling, exercise-related recovery, cardiovascular wellness, and other areas.
The research has produced interesting findings, but results differ across studies. Amount, duration, participant health, and formulation can all change the outcome.
That last word, formulation, is easy to skip.
It may be the most important word on this page.
Why Take a Quercetin Supplement if Quercetin Is Found in Food?
Foods rich in quercetin come with fiber, vitamins, minerals, and hundreds of other plant compounds.
A capsule cannot replace that.
A quercetin supplement serves a different purpose. It provides a measured and repeatable amount that would be difficult to obtain from the same foods every day.
There is another difference.
Food contains quercetin in several chemical forms, including glycosides. Those forms may be absorbed differently from the plain quercetin aglycone found in many capsules. Human nutrition research has found that food form can influence absorption.
Once quercetin is concentrated into a supplement, the label needs closer inspection.
The word “quercetin” alone does not tell you enough.
The Problem With Plain Quercetin
Plain quercetin does not dissolve easily in water.
That matters because the digestive system relies heavily on water-based fluids. Poor solubility can limit how much of an ingredient becomes available for absorption.
Quercetin is also rapidly transformed after intake.
A recent systematic review described poor oral bioavailability as a major challenge, linked with intestinal processing and rapid metabolism.
A human pilot study comparing different quercetin formulations also found that formulation strongly affected blood concentrations.
This does not mean plain quercetin provides no value.
It means the number printed on the bottle cannot tell the full story.
Imagine buying two raincoats.
One uses twice as much fabric, but the seams leak.
The other uses less material with a design built to keep water out.
Counting fabric alone would lead to the wrong comparison.
Quercetin works the same way. The amount matters, but delivery design matters too.
What Does Bioavailability Mean?
Bioavailability describes how much of a swallowed compound becomes available in the body and how it appears over time.
Researchers may measure:
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Peak blood concentration
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Total blood exposure
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Time needed to reach the highest concentration
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How long measurable compounds remain present
A formula with greater bioavailability may produce higher blood exposure from a lower raw amount.
That does not guarantee a stronger personal result.
Absorption data and health outcomes answer different questions.
Still, absorption is a logical place to begin. A supplement cannot support its intended role unless the body can access at least part of it.
Quercetin With Bromelain: What Does the Pairing Mean?
Search for quercetin supplements, and you will quickly find quercetin with bromelain.
Bromelain is a group of enzymes sourced from pineapple.
Some brands include it for its own research-backed characteristics. Others describe it as a companion for quercetin.
There is nothing inherently wrong with the pairing.
The evidence needs to be described accurately.
One older human study examined quercetin in men and included an open-label follow-up using a formula containing quercetin, bromelain, and papain. Since all three appeared in the same product, the study could not isolate how bromelain changed quercetin absorption.
That leaves shoppers with an important distinction.
Quercetin With Bromelain
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Combines quercetin with a pineapple-derived enzyme
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May appeal to shoppers who want both compounds
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Does not automatically mean the quercetin itself uses an enhanced delivery form
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Has limited direct human data isolating bromelain’s effect on quercetin absorption
Quercetin Phytosome
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Combines quercetin with phospholipids
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Changes how quercetin is dispersed and delivered
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Has been directly compared with plain quercetin in a human absorption study
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Is designed around quercetin’s solubility challenge
These are two different approaches.
The best choice depends on what you want from the formula.
What Is Quercetin Phytosome?
Quercetin Phytosome combines quercetin with phospholipids.
Phospholipids are fat-like components that form an important part of cell membranes. They have properties that help them interact with both water and fat.
In a phytosome, they help a plant compound disperse more effectively during digestion.
Omre’s Quercetin Phytosome uses:
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Quercetin from Sophora japonica
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A sunflower-derived phospholipid complex
This is not the same as placing plain quercetin beside sunflower oil in a capsule.
The quercetin and phospholipid components form a specific delivery complex.
What Did the Human Absorption Study Find?
A randomized crossover study compared Quercetin Phytosome with unformulated quercetin in healthy adults.
Participants received several quercetin formulations. Researchers then measured quercetin and related compounds in the blood over time.
The phytosome formulation produced substantially greater total exposure and peak blood concentrations than unformulated quercetin. The researchers also reported that the formulation was well tolerated during the study.
This is why comparing products by raw milligrams can be misleading.
A plain 1,000 mg quercetin serving and a 500 mg Quercetin Phytosome serving are not interchangeable.
The labels may share the same ingredient name, but the delivery designs differ.
Does Higher Absorption Mean Better Results?
An absorption study shows that more quercetin-related compounds reached the blood under the study conditions.
It does not prove that every buyer will experience a certain improvement.
Health outcomes depend on:
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The goal being studied
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The participant group
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The amount
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The study duration
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Diet and activity
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The outcome researchers measured
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Individual biology
Better absorption solves one part of the formula puzzle.
It does not solve the entire puzzle.
Still, when you are comparing quercetin supplements, using a form that directly addresses poor solubility is a rational starting point.
Why We Pair Quercetin With Fisetin
At Omre, we designed our formula for healthy aging and cellular wellness.
That is why we pair Quercetin Phytosome with fisetin rather than bromelain.
Fisetin is another plant flavonoid. It is found in small amounts in strawberries, apples, grapes, and several other foods.
Fisetin and quercetin share some structural features, but they are not the same compound.
Both have been studied in connection with:
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Antioxidant activity
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Cellular signaling
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Responses to everyday cellular stress
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Pathways related to cellular senescence
Fisetin has attracted particular interest in cellular senescence research. Much of that evidence comes from laboratory and animal studies, so it should not be presented as proof of a human longevity outcome.
The pairing gives the formula two related flavonoids with different research histories.
Quercetin brings broader human research and a known absorption challenge.
Fisetin contributes a growing body of healthy aging research.
What Is Inside Omre Quercetin + Fisetin?
Each two-capsule serving provides:
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500 mg Quercetin Phytosome
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100 mg fisetin at 98% purity
One bottle contains 60 vegan capsules and provides 30 daily servings.
The quercetin comes from Sophora japonica and is combined with a sunflower-derived phospholipid complex.
The fisetin comes from Cotinus coggygria stem and leaf extract.
Every active amount appears clearly on the Supplement Facts panel.
There is no proprietary blend.
Why We Chose 500 mg of Quercetin Phytosome
We did not select the amount to win a label-number contest.
The goal was to use a meaningful amount of a specialized quercetin form backed by human absorption research.
Plain quercetin and Quercetin Phytosome should not be compared through milligrams alone.
The 500 mg serving gives the formula a substantial phytosome component while keeping the complete daily routine to two capsules.
That serving design matters.
A theoretically impressive formula is not much use when it requires six or eight capsules and ends up untouched in a cabinet.
Why We Chose 100 mg of Fisetin
No universal daily fisetin amount has been established for healthy adults.
Research uses different amounts and schedules for different goals. Some studies examine daily use. Others examine larger short-term intakes.
We chose 100 mg of fisetin at 98% purity for a simple daily formula.
That does not make 100 mg the required amount for every person.
It means you can see:
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The exact serving
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The stated purity
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The source
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The companion ingredient
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The intended routine
Clarity beats a mystery dose every time.
Why We Keep the Formula Focused
Some quercetin supplements contain:
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Quercetin
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Bromelain
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Vitamin C
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Zinc
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Elderberry
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Nettle
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Turmeric
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Green tea
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Several herbs
A broad formula may suit someone who wants those ingredients together.
It also makes comparison harder.
Each added ingredient takes up room in the serving. Sometimes the panel becomes so crowded that several components appear in modest quantities.
Omre Quercetin + Fisetin uses two active ingredients:
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Quercetin Phytosome
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High-purity fisetin
The formula has one clear purpose.
You do not need to guess which ingredient carries the product.
Third-Party Testing Changes the Question
A label tells you what a company plans to put in the bottle.
Testing helps check the finished capsules.
Omre Quercetin + Fisetin undergoes third-party testing for:
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Ingredient amount
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Purity
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Bacteria
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Fungus
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Heavy metals
The product is made in the USA under GMP manufacturing standards.
Our wider brand approach centers on research-backed amounts, absorbable ingredient formats, and quality testing rather than underdosed proprietary mixtures.
Testing cannot promise that everyone will notice the same experience.
It answers basic purchasing questions first:
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Does the finished product meet its listed specifications?
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Has it been checked for unwanted contaminants?
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Is the quality discussion supported by documentation?
Those questions should not be buried at the bottom of a product page.
What a High-Quality Quercetin Supplement Should Show
Before buying quercetin, check these seven details.
1. The Quercetin Form
Look past the ingredient name.
Is it:
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Plain quercetin?
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Quercetin dihydrate?
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Quercetin Phytosome?
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A different enhanced-delivery form?
The form may affect absorption.
2. The Full Serving Amount
Check how many capsules create the listed amount.
A front label may show 1,000 mg while the directions require four or six capsules.
Omre provides its full serving in two vegan capsules.
3. Supporting Ingredients
Ask why each ingredient is present.
A companion should contribute to the product’s intended purpose, not simply lengthen the label.
4. Purity Details
Purity is especially valuable for concentrated plant compounds such as fisetin.
Omre states 98% purity for its fisetin.
5. Finished-Product Testing
Look for testing that goes beyond raw ingredient paperwork.
Useful checks include:
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Amount
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Purity
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Microbial quality
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Heavy metals
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Other contaminants
6. Manufacturing Standards
Look for clear production information.
Omre Quercetin + Fisetin is made in the USA under GMP standards.
7. Realistic Claims
A serious supplement brand should explain both the research and its limits.
A capsule can support a wellness routine.
It cannot replace sleep, movement, balanced nutrition, or professional care.
Who May Prefer Quercetin With Bromelain?
A quercetin with bromelain product may make sense for someone who:
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Specifically wants bromelain
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Prefers a pineapple-derived enzyme in the same formula
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Is not seeking fisetin
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Has reviewed the exact amounts of both ingredients
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Is comfortable with the quercetin form provided
The pairing is not wrong.
It serves a different formula goal.
Who May Prefer Omre Quercetin + Fisetin?
Omre may suit someone who:
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Wants a specialized quercetin delivery form
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Values direct human absorption research
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Wants quercetin paired with fisetin
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Prefers 98% pure fisetin
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Wants a focused two-ingredient formula
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Looks for finished-product testing
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Prefers vegan and gluten-free capsules
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Wants only two capsules per day
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Is building a healthy aging routine
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Wants a 30-day money-back guarantee
The strongest reason to choose Omre is not that every other quercetin product falls short.
It is that our formula takes a distinct approach.
We address quercetin absorption through a phytosome complex, then pair it with high-purity fisetin.
Do Not Choose Quercetin by Milligrams Alone
A label can make quercetin shopping look like a simple numbers game.
It is not.
The final decision comes down to five questions:
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What form does the product use?
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How does it address absorption?
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What companion ingredient supports the formula’s purpose?
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Has the finished product been tested?
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Is the routine easy enough to follow?
Omre Quercetin + Fisetin was built around those questions.
Each daily serving provides:
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500 mg Quercetin Phytosome
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100 mg fisetin at 98% purity
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Two vegan capsules
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Third-party testing
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30 servings per bottle
No hidden blend.
No need to buy separate quercetin and fisetin bottles.
No claim that one formula can do the work of an entire healthy lifestyle.
Simply a focused combination designed around absorption, transparency, and cellular wellness.
See Omre Quercetin + Fisetin, Review the Formula, and Check the Current Offer
Frequently Asked Questions
What is quercetin?
Quercetin is a plant flavonoid found in foods such as onions, apples, berries, capers, kale, grapes, and tea. Researchers have studied it for antioxidant activity, cellular signaling, exercise-related recovery, and several other wellness areas.
What is the best quercetin supplement?
There is no single best quercetin supplement for every adult. Look at the quercetin form, human absorption data, serving size, companion ingredients, finished-product testing, manufacturing details, and cost per serving.
Is Quercetin Phytosome better than regular quercetin?
A human absorption study found that Quercetin Phytosome produced substantially greater blood exposure and peak concentrations than unformulated quercetin. That supports its use as a higher-bioavailability format, but it does not guarantee a stronger personal result. (1)
What is quercetin with bromelain?
Quercetin with bromelain combines quercetin with a pineapple-derived enzyme. The two may be selected for their separate properties, but limited direct human evidence isolates bromelain’s effect on quercetin absorption.
Does Omre contain bromelain?
No. Omre pairs Quercetin Phytosome with fisetin. The formula is designed around healthy aging, cellular wellness, and quercetin absorption rather than a bromelain combination.
Why does Omre include fisetin?
Fisetin is a related plant flavonoid with growing research interest around antioxidant activity, cellular signaling, and cellular senescence. Omre provides 100 mg of fisetin at 98% purity alongside 500 mg of Quercetin Phytosome.
Can I get enough quercetin from food?
Foods such as onions, apples, berries, and capers provide quercetin along with many other nutrients. A supplement provides a larger, measured amount, but it should complement a balanced diet rather than replace quercetin-rich foods.
References
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Riva A, et al. Improved Oral Absorption of Quercetin From Quercetin Phytosome, a New Delivery System Based on Food Grade Lecithin. https://pmc.ncbi.nlm.nih.gov/articles/PMC6418071/
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Solnier J, et al. A Pharmacokinetic Study of Different Quercetin Formulations in Healthy Participants. https://pmc.ncbi.nlm.nih.gov/articles/PMC10435304/
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Dabeek WM, Marra MV. Dietary Quercetin and Kaempferol: Bioavailability and Potential Cardiovascular-Related Bioactivity in Humans. https://pmc.ncbi.nlm.nih.gov/articles/PMC6835347/
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Frenț OD, et al. Quercetin, Secondary Metabolite of the Flavonoid Group, as a Bioactive Compound in Human Health. https://pmc.ncbi.nlm.nih.gov/articles/PMC11594109/
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Andres S, et al. Safety Aspects of the Use of Quercetin as a Dietary Supplement. https://pubmed.ncbi.nlm.nih.gov/29127724/
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Shoskes DA, et al. Quercetin in Men With Category III Chronic Prostatitis. https://pubmed.ncbi.nlm.nih.gov/10604689/
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Aghababaei F, Hadidi M. Recent Advances in Potential Health Benefits of Quercetin. https://pmc.ncbi.nlm.nih.gov/articles/PMC10384403/
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Omre Quercetin + Fisetin Product Information. https://omre.co/products/quercetin-fisetin
About the medical reviewer
Dr. Sara Alisha Khan, MD, PGDMLE
Table of contents
- What Is Quercetin?
- Why Take a Quercetin Supplement if Quercetin Is Found in Food?
- The Problem With Plain Quercetin
- What Does Bioavailability Mean?
- Quercetin With Bromelain: What Does the Pairing Mean?
- What Is Quercetin Phytosome?
- What Did the Human Absorption Study Find?
- Does Higher Absorption Mean Better Results?
- Why We Pair Quercetin With Fisetin
- What Is Inside Omre Quercetin + Fisetin?
- Why We Keep the Formula Focused
- Third-Party Testing Changes the Question
- What a High-Quality Quercetin Supplement Should Show
- Who May Prefer Quercetin With Bromelain?
- Who May Prefer Omre Quercetin + Fisetin?
- Do Not Choose Quercetin by Milligrams Alone
- Frequently Asked Questions
- References