Is Tru Niagen Worth It? 5 NAD+ Bottles Held to the Same Checks
Updated on Oct 5, 2026
Medically reviewed by Dr. Sara Alisha Khan, MD, PGDMLE— Written by Dr. Sara Alisha Khan, MD, PGDMLE
Updated on Oct 5, 2026
Table of contents
Tru Niagen is the best-known NR bottle, so here's how it scores against four rivals on five checks.
You've likely read the Niagen studies. Maybe you take Tru Niagen now, or you're close to ordering it.
You compare labels before you buy. Most people who take NAD+ seriously do.
We make one of these.
So we held Tru Niagen and four other bottles to the same five checks we built ours to pass.
First, a fair look at Tru Niagen. Then the checks. Then the ranking.
Tru Niagen, checked fairly
It has real strengths.
NR raised blood NAD+ in human trials. In 140 healthy adults aged 40 to 60, 300 mg a day lifted it within 2 weeks and held it for 8 weeks.
Niagen is the form most published NR studies use, per its website.
Three things are missing. No purity percentage for its NR is published. There is no partner ingredient. And refunds cover sealed, unopened bottles only, checked Oct 2026.
Those three gaps decide where it ranks.
What most NAD+ labels leave out
NAD+ falls with age. In skin from people aged 0 to 77, levels were lower in older adults.
Two precursors raised it in human trials. NMN at 250 to 1,200 mg a day. NR at 100 to 1,000 mg a day.
All five bottles here get the dose right. The gaps sit elsewhere.
The 5 checks that matter
Use these on any bottle, ours included.
How the top 5 compare
One-time price ÷ 30 servings, at time of writing, checked Oct 2026. Ties go to the lower cost.
| Product | Trial dose | Lab proof | Purity % | Partner | Opened refund | Passed | Key dose | Cost/day |
|---|---|---|---|---|---|---|---|---|
| Omre NMN + Resveratrol Our pick |
✓ | ✓ | ✓ | ✓ | ✓ | 5 of 5 | 500 mg NMN | $2.30 |
| Life Extension NAD+ Cell Regenerator | ✓ | ✓ | – | – | ✓ | 3 of 5 | 300 mg NR | $1.35 |
| Elysium Basis | ✓ | ✓ | – | ✓ | – | 3 of 5 | 250 mg NR | $2.17 |
| ProHealth NMN Pro Complete | ✓ | – | ✓ | – | ✓ | 3 of 5 | 1,000 mg NMN | $2.87 |
| Tru Niagen 300mg | ✓ | ✓ | – | – | – | 2 of 5 | 300 mg NR | $1.63 |
Swipe the table sideways to see every column →
Tru Niagen and 4 rivals, ranked
Our pick is Omre NMN + Resveratrol, the only one of the five that passes every check.
1. Omre NMN + Resveratrol: Passes all five checks
"I can tell if I forget taking it in the morning, amazing energy whole day."
Ruth B., verified buyer
500 mg of NMN sits inside the range human trials used. It is paired with 500 mg of micronized trans-resveratrol, with BioPerine® added for absorption.
Every batch is tested twice: raw ingredients first, then finished capsules.
The guarantee covers a bottle you've opened. You find out how it feels before you decide.
Start with one bottle, backed by 30 days →2. Life Extension NAD+ Cell Regenerator: Same Niagen, lower price
3. Elysium Basis: NR plus partner, final sale
4. ProHealth NMN Pro Complete: Highest doses, scope unnamed
5. Tru Niagen 300mg: Strong lab proof, single ingredient
The proof behind our #1
Omre was founded by Dr. Pedram Kordrostami, a London-trained medical doctor who practiced in the NHS, for his family.
Every batch is tested twice before it reaches you.
Raw ingredients first, then finished capsules, for dose, purity, heavy metals and microbes. The third-party test results are on the product page.
Featured in Forbes · Yahoo Life · GQ · Healthline
Made in the USA in a GMP-certified, FDA-registered facility.
Fortune named it the Best Vegan NMN Supplement of 2026.
HSA/FSA eligible through Truemed. 30-day money-back guarantee.
Reviewers notice more than energy. Asked what changed, 173 chose less brain fog and 118 chose better recovery.
See the lab report on the product page →
Questions before you buy
Is NMN better than NR?
Both are NAD+ precursors, and both raised blood NAD+ in human trials. Choose by the five checks. Omre pairs NMN with resveratrol, which supports NAD+-dependent sirtuin pathways.
Is NMN legal in supplements?
Yes. In September 2025, the FDA confirmed NMN is not excluded from the definition of a dietary supplement. Like every supplement, NMN and NR are not FDA-approved.
Why pay more than Tru Niagen?
Tru Niagen is $1.63 a day and passes two checks. Omre is $2.30 a day and passes five, including a refund on an opened bottle. In our last customer survey, 93% said evidence matters more to them than price.
Can I take it with my medications?
Do not use it if you are pregnant, nursing or under 18. On prescription medication, especially blood thinners, blood pressure or diabetes medication? Ask your doctor first.
Do I have to subscribe?
No. One-time purchase is $69. Autoship & Save takes 5% off 1 month, 10% off 3 months, or 20% off 6 months. Cancel, skip or pause anytime.
The bottom line
Choose the bottle that passes the most checks. Then compare price.
Omre NMN + Resveratrol is the only one of the five that passes all five. It pairs over 99% pure NMN with micronized resveratrol, and every batch is tested twice. Its 30-day money-back guarantee covers an opened bottle.
Choose your supply below, one-time or Autoship ↓
- DMDaniel M.Verified BuyerReviewingNMN + ResveratrolI recommend this productAge Range 55-64Gender MaleHow Longevity Helped? More EnergyRated 5 out of 5 stars3 years agoThis stuff changed my life!!!!!
Ok, this was recommended to me by my doctor - yes, you heard that right! My actual doctor told me to start taking this - This EXACT brand! Because it has the Resvirotrol (spelling?) also in it which she said was important.
Normally I don’t go for these types if things but I trust my doctor implicitly so I ordered it.
I’ve been taking two pills per day for one month now… let me tell you what’s been happening to my body…
I’m a 56 year old guy - I workout a lot - I’m a retired Airline Pilot and I’ve always been I pretty good shape but this stuff has rocketed me into a new sphere of training I though I had left behind 35 years ago! Yes, it’s that good!
Since taking this stuff my workouts last 50% longer and they’re at least 50% more intense!!! I’m not exaggerating!!!!! Even my wife has noticed! I lift heavier, my hikes are way longer and I don’t experience DOMS afterwards.
Somehow I have more energy during the day and it lasts all day. Mind officially blown!!!
This stuff works! I am SO grateful that my doc recommended this to me… it’s not cheap! But I’ll be buying this forever!
BTW - I’m not paid or endorsed in any way by these guys or their company! I don’t know them in any way and I have zero connection to them other than getting my order in the mail from them. (Shipping was not extremely fast though - that sucked).
This stuff is amazing!!!!! Anyone reading this - try it! You can thank me later.
D.M.
- ALANDREW L.Verified BuyerReviewingNMN + ResveratrolI recommend this productAge Range 65+Gender MaleHow Longevity Helped? More EnergyRated 5 out of 5 stars2 years agoLiving more!
Great product I feel full of energy now that I’m taking NMN
- EMEileen M.Verified BuyerReviewingNMN + ResveratrolI recommend this productAge Range 45-54Gender FemaleHow Longevity Helped? More EnergyRated 5 out of 5 stars3 years agoStaying youthful!
I’ve been told I don’t look my age at 53, I do take care of myself from the inside out! I’m adding this NMN+RESVERATROL to my regimen to staying youthful & more. I have been taking a month now & plan on sticking to it♥️
- CLCheryl L.Verified BuyerReviewingNMN + ResveratrolI recommend this productAge Range 55-64Gender FemaleHow Longevity Helped? More Energy, Easy dosingRated 5 out of 5 stars2 years agoRenewed Energy and Life Force
I was told I have autoimmune Hashimoto's in 2020 after I got COVID at 56 years old. I can't even begin to tell you how bone numbing and cell deep my fatigue was, and even worse, NOTHING helped. Not medication, doctors, handfuls of supplements, acupuncture, or Reiki. I could barely get off my couch or out of my bed just to purchase a few groceries , or take a shower. I thought that was going to be my life, forever, which dropped me into depression and a feeling of utter hopelessness. I researched and researched on my own and decided I'd give one more thing a shot, and that was OMRE's Resveritrol and NMN. Within 5 days of taking my first two pills, after being so ill for three years, I had the energy to get out of bed, take a shower, and I actually cooked myself a meal. Within two weeks, I could do that, AND mow my yard, or work a normal day without having to take a nap. Best of all, I actually WANTED to get up, where prior to taking the supplements, I didn't even want to wake up, let alone try to do anything more than just breathe. This supplement gave me a large portion of my life back. I still have a few “down days†a month because Hashimoto's doesn't just go away, but those days are days where all I do is take a nap, and resume my normal life straight away after it. Yes, they are on the expensive side (and being on a low fixed retirement income, hard to afford), but the benefits far, far outweigh the price. I couldn't recommend trying something more than I do this…
- SEstephen e.Verified BuyerReviewingNMN + ResveratrolI recommend this productAge Range 55-64Gender MaleHow Longevity Helped? Easy dosingRated 5 out of 5 stars2 years agoLongevity and energy
I bought these after reading others reviews and the independent testing that’s been done. I follow David Sinclair and his approach for longevity and health.
It’s early days, just over a month so far I feel good, my skin appears clearer and I don’t appear to have any side affects.
I’ll continue with the capsules.