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I Thought I Was Doing Everything Right to Stay Energized After 40. Then I Learned My Energy Wasn't Declining. It Was Changing.

Updated on May 19, 2026
I Thought I Was Doing Everything Right to Stay Energized After 40. Then I Learned My Energy Wasn't Declining. It Was Changing.
Medically reviewed by Dr Pedram Kordrostami, MD— Written by Dr. Dominic Gartry, MD
Updated on May 19, 2026

Table of contents

I still show up.

Five days a week, sometimes six. Pilates. Weights. The occasional 6am run I swore I'd never do again. I watch what I eat. I sleep seven hours. I do all the things people tell you to do.

So why, sometime around 43, did I start feeling like I was running on a half-charged battery?

Not exhausted. Not sick. Just... less. Like someone had quietly turned a dial down on everything I used to count on. My workouts felt harder at the same intensity. My recovery took a day longer than it should. By 3pm I was going through the motions, not powering through them.

I kept waiting for it to pass. Thought maybe I needed more iron. Different sleep. Less stress.

I wasn't wrong to try all of that. I was just missing the bigger picture.

Here's what nobody tells you when you're in your 40s and still showing up for your health every single day.

Your body isn't breaking down. Your cells are burning fuel differently.

There's a molecule inside every cell in your body called NAD+. It's the fuel source behind almost every process that makes you feel energized, sharp, and physically capable. Your muscles run on it. Your brain runs on it. Your ability to recover from a hard workout runs on it.

In your 20s, you had plenty. You didn't notice it because you didn't need to.

By your 40s, research suggests NAD+ levels have dropped by roughly half compared to where they were two decades earlier. By your 50s, that gap widens further.

This isn't a theory. It's been measured. Researchers at Washington University School of Medicine, the University of Colorado, and institutions like the Sinclair Lab at Harvard have spent the better part of the last decade documenting what happens to NAD+ as we age. And the picture is consistent.

It doesn't mean you're falling apart. It means the system that powers your cells is working with less fuel than it used to.

That's a very different problem. And it has a very different solution.

I'm not someone who buys into trends. I spent a long time on the skeptical side of the supplement world, mostly because I'd tried enough products that promised a lot and delivered nothing. The bar for me had gotten high.

What shifted my thinking wasn't a testimonial. It was the underlying biology.

NMN, short for Nicotinamide Mononucleotide, is a precursor to NAD+. Your body converts it directly. That's not marketing language, that's the metabolic pathway. And unlike a lot of supplement claims that rest on one small study and a lot of hope, NMN has been through multiple human trials now, not just animal models.

A 2022 clinical trial published in the journal npj Aging, involving healthy adults, showed measurable increases in NAD+ levels in the blood following NMN supplementation. A separate trial out of Washington University documented improved muscle function and insulin sensitivity in postmenopausal women specifically. These are peer-reviewed outcomes in humans, in the relevant age group.

That last part matters. Because a lot of longevity research is done on 25-year-olds or on mice. Research in women over 40 is rarer, and that's exactly the demographic where the NAD+ gap starts to really show up.

What I noticed when I started taking NMN wasn't dramatic. It wasn't a lightning bolt moment.

It was more like the afternoon arrived and I hadn't started fading yet. My post-workout soreness, which had been lasting 48 hours or more, settled back down to something manageable. I stopped dreading the second half of my day. Focus held longer. I wasn't reaching for caffeine at 2pm just to get through a call.

Months in, a few things I hadn't expected: my sleep felt deeper, not longer, just more restorative. My skin, which I'd been quietly writing off as a consequence of my 40s, had more bounce to it. I'm not claiming NMN is a skincare product. But it makes sense. If your cells are better resourced, that shows up everywhere.

The hard part of this conversation is that the supplement industry has badly polluted the NMN category. There are products on shelves with no third-party testing, no transparent sourcing, no evidence their NMN is even bioavailable by the time it reaches your bloodstream. Some studies on NMN absorption have shown that capsule formulation matters significantly. Purity matters. Dosing matters.

I take Omre NMN + Resveratrol. The reason isn't loyalty, it's specifics.

Every batch is third-party tested and the certificates of analysis are published, not buried in a footnote. The dosing is based on the human clinical trial range, not a number someone picked because it sounds impressive. It's manufactured in a GMP-certified facility in the US. They're not the cheapest option and they know it. They're not trying to compete on price. They're competing on the thing that actually matters: whether it works.

If you've been doing everything right and still feel like something is slightly off, the problem probably isn't your discipline. It isn't your willpower. It isn't that you're just getting older and this is how it goes now.

It might be your cells running on less than they should be.

That's a solvable problem.

If you're 40 or older and you train regularly, take care of yourself, and still can't shake the feeling that something is running at 70 percent when it used to run at 100, this is worth looking at seriously.

Start with the research. Read the Washington University trial. Look at the ingredient label and the COA before you buy anything. And if you want to know where I landed after doing exactly that, Omre is the link below.

Not because you need to be convinced. Because you've already done the hard part. You just need the right fuel.

Medically reviewed by
Dr Pedram Kordrostami, MD

Dr. Pedram Kordrostami, M.D. is a London-trained medical doctor who graduated from Queen Mary University of London (2016). He practiced within the National Health Service (NHS), gaining clinical experience across General Internal Medicine, Dermatology, and Emergency Medicine (A&E). Dr. Kordrostami now specializes in evidence-based anti-aging medicine and longevity science. GMC number: 7528786.

Table of contents

NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol

NMN + Resveratrol

NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol
NMN + Resveratrol

MD-formulated NAD+ booster with 500mg 99% pure NMN, 500mg 98% pure micronized trans-resveratrol, and 5mg BioPerine® for daily cellular energy, healthy aging, and vitality support. All at research-backed doses.*

Servings | per serving
Supply
OR
“As a medical professional, I value Omre’s focus on evidence-based supplementation and bioavailable ingredients. It’s refreshing to see a brand that prioritizes clarity, trust, and real results.”
Dr. Sara Alisha Khan
Medical Doctor (MD)
Real People, Real Results
Suggested Use

Take 2 capsules in the morning, with food, for best results.

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1,543 reviews
  • DM Profile picture for Daniel M.
    Daniel M.
    Verified Buyer
    Reviewing
    NMN + Resveratrol
    I recommend this product
    Age Range 55-64
    Gender Male
    How Longevity Helped? More Energy
    Rated 5 out of 5 stars
    3 years ago
    This stuff changed my life!!!!!

    Ok, this was recommended to me by my doctor - yes, you heard that right! My actual doctor told me to start taking this - This EXACT brand! Because it has the Resvirotrol (spelling?) also in it which she said was important.

    Normally I don’t go for these types if things but I trust my doctor implicitly so I ordered it.

    I’ve been taking two pills per day for one month now… let me tell you what’s been happening to my body…

    I’m a 56 year old guy - I workout a lot - I’m a retired Airline Pilot and I’ve always been I pretty good shape but this stuff has rocketed me into a new sphere of training I though I had left behind 35 years ago! Yes, it’s that good!

    Since taking this stuff my workouts last 50% longer and they’re at least 50% more intense!!! I’m not exaggerating!!!!! Even my wife has noticed! I lift heavier, my hikes are way longer and I don’t experience DOMS afterwards.

    Somehow I have more energy during the day and it lasts all day. Mind officially blown!!!

    This stuff works! I am SO grateful that my doc recommended this to me… it’s not cheap! But I’ll be buying this forever!

    BTW - I’m not paid or endorsed in any way by these guys or their company! I don’t know them in any way and I have zero connection to them other than getting my order in the mail from them. (Shipping was not extremely fast though - that sucked).

    This stuff is amazing!!!!! Anyone reading this - try it! You can thank me later.

    D.M.

    EfficacyRated 5.0 on a scale of 1 to 5
    Ease of UseRated 5.0 on a scale of 1 to 5
    ValueRated 4.0 on a scale of 1 to 5
  • AL
    ANDREW L.
    Verified Buyer
    Reviewing
    NMN + Resveratrol
    I recommend this product
    Age Range 65+
    Gender Male
    How Longevity Helped? More Energy
    Rated 5 out of 5 stars
    2 years ago
    Living more!

    Great product I feel full of energy now that I’m taking NMN

    EfficacyRated 5.0 on a scale of 1 to 5
    Ease of UseRated 5.0 on a scale of 1 to 5
    ValueRated 4.0 on a scale of 1 to 5
  • EM
    Eileen M.
    Verified Buyer
    Reviewing
    NMN + Resveratrol
    I recommend this product
    Age Range 45-54
    Gender Female
    How Longevity Helped? More Energy
    Rated 5 out of 5 stars
    3 years ago
    Staying youthful!

    I’ve been told I don’t look my age at 53, I do take care of myself from the inside out! I’m adding this NMN+RESVERATROL to my regimen to staying youthful & more. I have been taking a month now & plan on sticking to it♥️

    EfficacyRated 5.0 on a scale of 1 to 5
    Ease of UseRated 5.0 on a scale of 1 to 5
    ValueRated 4.0 on a scale of 1 to 5
  • CL
    Cheryl L.
    Verified Buyer
    Reviewing
    NMN + Resveratrol
    I recommend this product
    Age Range 55-64
    Gender Female
    How Longevity Helped? More Energy, Easy dosing
    Rated 5 out of 5 stars
    2 years ago
    Renewed Energy and Life Force

    I was told I have autoimmune Hashimoto's in 2020 after I got COVID at 56 years old. I can't even begin to tell you how bone numbing and cell deep my fatigue was, and even worse, NOTHING helped. Not medication, doctors, handfuls of supplements, acupuncture, or Reiki. I could barely get off my couch or out of my bed just to purchase a few groceries , or take a shower. I thought that was going to be my life, forever, which dropped me into depression and a feeling of utter hopelessness. I researched and researched on my own and decided I'd give one more thing a shot, and that was OMRE's Resveritrol and NMN. Within 5 days of taking my first two pills, after being so ill for three years, I had the energy to get out of bed, take a shower, and I actually cooked myself a meal. Within two weeks, I could do that, AND mow my yard, or work a normal day without having to take a nap. Best of all, I actually WANTED to get up, where prior to taking the supplements, I didn't even want to wake up, let alone try to do anything more than just breathe. This supplement gave me a large portion of my life back. I still have a few “down days” a month because Hashimoto's doesn't just go away, but those days are days where all I do is take a nap, and resume my normal life straight away after it. Yes, they are on the expensive side (and being on a low fixed retirement income, hard to afford), but the benefits far, far outweigh the price. I couldn't recommend trying something more than I do this…

    EfficacyRated 5.0 on a scale of 1 to 5
    Ease of UseRated 5.0 on a scale of 1 to 5
    ValueRated 5.0 on a scale of 1 to 5
  • SE
    stephen e.
    Verified Buyer
    Reviewing
    NMN + Resveratrol
    I recommend this product
    Age Range 55-64
    Gender Male
    How Longevity Helped? Easy dosing
    Rated 5 out of 5 stars
    2 years ago
    Longevity and energy

    I bought these after reading others reviews and the independent testing that’s been done. I follow David Sinclair and his approach for longevity and health.

    It’s early days, just over a month so far I feel good, my skin appears clearer and I don’t appear to have any side affects.

    I’ll continue with the capsules.

    EfficacyRated 4.0 on a scale of 1 to 5
    Ease of UseRated 5.0 on a scale of 1 to 5
    ValueRated 4.0 on a scale of 1 to 5