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The best NAD supplement for women is one that supports energy, skin health, and graceful aging using clean, research-backed ingredients. These supplements often include compounds like NMN or NR, which help the body naturally restore its NAD+ levels.
As women age, NAD+ levels begin to decline, which may lead to tiredness, brain fog, slower metabolism, or visible signs of aging.
In this article, we’ve reviewed 5 top NAD+ supplements that are especially supportive for women’s wellness goals, whether that’s maintaining focus, balancing hormones, or feeling more energized throughout the day.
Cellular NAD+ booster with ultra-pure NMN and Resveratrol, at research-backed doses.*
NMN + RESVERATROL
Best NAD Supplement for Women: Our Top Picks
Best Overall for Women: Omre NMN + Resveratrol
Best for Hormone Support: Wonderfeel Youngr NMN
Best Clinically Proven NR Option: Tru Niagen
Best for Active Lifestyles: Thorne NiaCel 400
Best for Skin and Aging: Elysium Basis
Here’s a quick look at how these supplements compare in terms of NAD+ form, ingredients, and price:
1. Best Overall NAD Supplement for Women – Omre NMN + Resveratrol
Omre’s NMN + Resveratrol formula is one of the most balanced and reliable NAD supplements for women in 2025. It combines 500 mg of NMN with 500 mg of Resveratrol, which together support healthy aging, energy production, and focus.
To help your body absorb it better, it also includes BioPerine®, a black pepper extract shown to increase the absorption of Resveratrol and other nutrients.
This supplement is third-party tested, made in a GMP-certified facility, and uses 99% pure NMN. The Resveratrol is also high-purity (98%).
You’ll get a full 30-day supply per bottle. It works best when taken with a meal that includes some healthy fats.
Pros:
Clean, research-backed dosing with high-purity ingredients
Includes BioPerine® for better absorption
Supports energy, skin, and brain health
Great all-in-one daily formula
Cons:
Works best with dietary fat
Capsule form may not suit everyone
2. Best for Hormone Support – Wonderfeel Youngr NMN
Wonderfeel’s Youngr NMN is one of the few NAD+ supplements that goes beyond energy and aging support to also target hormone health and mood.
It includes 900 mg of NMN, along with Vitamin D3, Trans-Resveratrol, and Ergothioneine, all of which are beneficial for women, especially those over 35.
Vitamin D is known to help with hormonal balance and bone health, while Ergothioneine is a powerful antioxidant that supports long-term cell function.
The formulation was designed by a team of longevity researchers, making it one of the most well-rounded options for women focused on wellness and graceful aging.
Pros:
High NMN dose with proven antioxidant support
Includes Vitamin D, which supports hormonal balance
Great for mood, vitality, and metabolism
Science-backed and physician-formulated
Cons:
On the premium end of the price range
May be too strong for beginners
3. Best Clinically Proven NR Option – Tru Niagen
If you're looking for a NAD supplement that’s simple, clean, and backed by strong research, Tru Niagen is the one to consider.
It uses 300 mg of Niagen®, a patented form of Nicotinamide Riboside (NR), and is supported by more than a dozen human clinical studies. One of those studies showed it could raise NAD+ levels by over 50% in just two weeks.
This supplement is FDA GRAS-certified and made in NSF-certified facilities, which adds to its trust factor. It's a great choice for women who prefer a no-nonsense supplement without additional ingredients.
Pros:
Clinically proven to raise NAD+ levels
Simple, clean formula with patented NR
FDA GRAS and third-party tested
Reliable option for daily use
Cons:
No added antioxidants or extras
May not suit those looking for an all-in-one formula
4. Best for Active Lifestyles – Thorne NiaCel 400
Thorne’s NiaCel 400 is a favorite among women with busy or active routines.
It includes 415 mg of Nicotinamide Riboside (NR) along with TMG (trimethylglycine) to support methylation, a process that supports DNA repair and healthy detoxification.
This one is NSF Certified for Sport, so it’s trusted by athletes and professionals who need to avoid banned substances.
Whether you're working out regularly or juggling work, family, and fitness, this NAD+ supplement helps support recovery and long-lasting energy.
Pros:
Strong dose of NR with added methylation support
Trusted NSF certification for clean sports use
Good for energy, recovery, and metabolism
Professional-grade brand with excellent quality control
Cons:
No Resveratrol or antioxidant blend
A little pricey for just two main ingredients
5. Best for Skin and Aging – Elysium Basis
Elysium Basis is a great option for women who want to support healthy skin and aging from the inside out. It blends 250 mg of Nicotinamide Riboside (NR) with 50 mg of pterostilbene, a powerful antioxidant that’s similar to Resveratrol but with better bioavailability.
This dual-action formula is backed by human clinical research. In one study, it increased NAD+ levels by up to 40% in four weeks, which may help with cellular repair, energy production, and skin resilience. It’s also NSF Certified for Sport, so it meets strict quality and safety standards.
If you’re looking for a supplement that supports long-term skin health and graceful aging with clinical backing, this one checks all the boxes.
Pros:
Backed by clinical research showing NAD+ increase
Includes pterostilbene, an antioxidant linked to healthy aging
Great for skin, energy, and long-term cellular health
NSF Certified for Sport and safety-tested
Cons:
Lower NR dose than some competitors
Slightly higher price for the amount of active ingredients
NMN + RESVERATROL
Cellular NAD+ booster with ultra-pure NMN and Resveratrol, at research-backed doses.*
What Is NAD+?
NAD+ (short for Nicotinamide Adenine Dinucleotide) is a molecule found in every cell in your body that helps turn food into energy and supports cell repair. It plays a big part in how your body stays healthy, energized, and able to bounce back from stress.
As we age, NAD+ levels naturally go down, which can affect everything from how much energy you feel during the day to how well your body repairs itself.
It’s also linked to brain function, metabolism, and even how your skin looks and feels.
That’s why NAD+ has become a focus in the wellness and longevity space. Scientists are learning more about how boosting NAD+ may support healthy aging, better focus, and even longer healthspan, not just lifespan.
Why Women Might Need More Support
Women tend to experience unique changes in NAD+ levels due to hormonal shifts, especially during perimenopause and menopause. These changes can lead to lower energy, slower metabolism, brain fog, and more noticeable signs of aging.
On top of natural aging, stress, poor sleep, and lack of key nutrients can lower NAD+ even further. That’s where a quality NAD+ supplement might help.
Here are a few reasons women might benefit from extra NAD+ support:
Hormonal changes: Estrogen levels drop with age, and this shift can affect how cells produce energy. Supporting NAD+ may help improve that energy balance naturally (1).
Slower metabolism: Lower NAD+ has been linked to slower fat burning and more fatigue. Raising NAD+ might help keep your metabolism running more smoothly (2).
Brain fog and mood swings: Some studies suggest that boosting NAD+ can help with focus, memory, and stress resilience, which many women find helpful during hormonal transitions (3).
Skin and aging: NAD+ plays a role in repairing cells and supporting collagen production, both of which are key for youthful-looking skin (4).
Are NAD Supplements Safe for Women?
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NAD supplements are generally safe for women when taken as directed, especially those made with NMN or NR, which are both widely studied and well tolerated. These ingredients have been used in multiple clinical trials without serious side effects reported in healthy adults.
For example, a study found that daily supplementation with NR was safe over 8 weeks and effectively increased NAD+ levels without causing harm to liver or kidney function (5).
Another clinical trial on NMN in Endocrine Journal (2020) showed that 250 mg of NMN daily was well tolerated by middle-aged and older women, with no major side effects reported (6).
That said, just like with any supplement, some people may experience mild reactions, especially in the beginning. These might include:
Upset stomach or nausea
Headache
Fatigue in the first few days (as your body adjusts)
Digestive changes like bloating or loose stools
These usually go away on their own, but if they stick around or feel uncomfortable, it’s worth talking to a healthcare provider. It's also smart to be cautious if you're pregnant, nursing, or managing a medical condition.
How to Choose the Best NAD Supplement as a Woman
Finding the right NAD supplement doesn’t have to be complicated. Here are some key things to look at:
NMN vs NR: What’s Better for You?
Both NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside) help your body make NAD+, but they work slightly differently.
NMN is a step closer to NAD+ and may be absorbed more directly, especially as you get older. NR, on the other hand, has more human studies behind it and is often used in clinical trials.
For women focused on energy, skin, and hormone support, either can work. NMN is great if you want a faster-acting option, while NR might be better if you prefer a more researched, slow-build formula.
Look for Clean Formulas
Skip products with fillers, artificial dyes, or mystery blends. Stick with brands that list exact dosages and back up their ingredients with testing.
A clean formula means fewer side effects and more confidence in what you're taking.
Think About Absorption
Not all supplements absorb the same way. Powders and liposomal liquids may help your body absorb NAD+ precursors more easily.
Capsules are more convenient but might be a little slower to act. If you have trouble digesting capsules, a liquid or sublingual powder might be a better fit.
Choose Extras That Support Women’s Health
Some NAD supplements include helpful extras like Resveratrol (an antioxidant), Vitamin D (supports hormones and bones), or TMG (supports methylation and detox).
These can make a good supplement even better, especially for women managing hormonal changes or stress.
Conclusion
NAD+ plays a big role in how women feel, think, and age. As levels decline with age, the right supplement can help fill in the gaps, supporting energy, brain function, hormonal balance, and even skin health.
The five supplements listed here offer clean, trusted options to help you get more from your daily routine.
Whether you’re focused on graceful aging or just want more steady energy, there’s a formula that fits your needs.
If you're looking for one that checks all the boxes, Omre NMN + Resveratrol is a great place to begin. It’s well-dosed, well-tested, and works for a variety of wellness goals.
Check availability and see if it’s the right fit for your routine
FAQs
Is NAD safe for women to take daily?
Yes, NAD supplements made with NMN or NR are generally considered safe when taken at the suggested dose. Most people tolerate them well. That said, it's always a good idea to check with your doctor if you’re pregnant, breastfeeding, or taking medication, just to be sure it fits your personal health needs.
Does it help with menopause symptoms or fatigue?
While NAD+ supplements aren’t made specifically for menopause, some women do report feeling more steady energy, better focus, and less brain fog. This could be helpful during times when hormones are shifting. Everyone’s experience is different, though, so results may vary.
Can NAD+ supplements improve skin and hair?
There’s some early research showing that NAD+ plays a role in skin health and cell repair, which may support better skin texture and hydration over time. Some users also say their hair feels stronger, but there’s not enough research yet to say this for sure.
Should women under 30 take NAD supplements?
Most women under 30 still have naturally high levels of NAD+, so a supplement may not be needed unless you’re dealing with chronic stress, poor sleep, or recovery issues. If you're curious, starting with a lower dose or speaking to a health provider can help you decide if it’s the right time.