7 Best Resveratrol Supplements in 2025 for Longevity, Energy & Heart Health

How We Chose the Best Resveratrol Supplements

Choosing the best resveratrol supplement means looking beyond marketing labels. Our team reviewed dozens of products and focused on measurable factors that affect purity, potency, and long-term safety.

Here’s what we looked for:

• Purity above 98%: Only supplements using high-purity trans-resveratrol made from Japanese knotweed or red wine extract were included.

• Enhanced absorption: Liposomal delivery, micronized resveratrol, or BioPerine to improve bioavailability.

• Third-party testing: Verified safety, purity, and absence of heavy metals or fillers.

• Clinical relevance: Doses and ingredient combinations supported by human or preclinical studies.

• Value and transparency: Fair price per dose, clear labeling, and reputable sourcing.

We also considered verified customer feedback, certifications (like Informed-Sport or GMP), and whether each brand provided full disclosure of its formulation.

Best Resveratrol Supplement of 2025: Our Top Picks

• Best Overall Resveratrol Supplement: Omre NMN + Resveratrol

• Best Single-Ingredient Formula: PartiQlar Pure Resveratrol

• Purest Trans-Resveratrol Extract: Decode Age Resveratrol Supplement

• Best High-Dose Option: ProHealth Longevity Trans-Resveratrol Plus

• Best for Absorption: Purovitalis Liposomal Resveratrol

• Best Budget Pick: Nutricost Resveratrol 700 mg

• Best for Purity and Value: Toniiq Ultra High Purity Resveratrol

• Best Liposomal Capsule: Renue By Science LIPO Trans-Resveratrol

• Best for Athletes and Recovery: Momentous Resveratrol

• Best for Skin and Anti-Aging: Reserveage Resveratrol Beauty 500 mg

• Best Whole-Food Formula: Garden of Life Raw Resveratrol

Here’s a quick side-by-side comparison of the best resveratrol supplements in 2025 to help you make the right choice.

1. Best Overall Resveratrol Supplement: Omre NMN + Resveratrol

Key Details:

• Ingredients: 500 mg NMN, 500 mg micronized trans-resveratrol, 5 mg BioPerine

• Price: Around $59.97 for a 30-day supply

• Ideal for: People looking for energy, longevity, and cellular health support

At Omre, we wanted to create more than just a resveratrol supplement; we set out to build a complete cellular energy formula. 

Our NMN + Resveratrol blend combines two of the most researched ingredients for healthy aging: NMN, a direct NAD+ precursor that supports energy and repair, and trans-resveratrol, a powerful polyphenol that activates sirtuins linked to longevity and cell protection.

Each serving contains clinically studied doses of both nutrients, enhanced with BioPerine for better absorption. The result is a clean, science-backed supplement that helps support focus, energy, and long-term vitality. 

Whether you’re optimizing for performance or healthy aging, our formula is designed to deliver results you can feel.

Pros:

• Combines NMN and resveratrol for dual cellular support

• Micronized for better absorption

• Doctor-formulated and third-party tested

• Includes BioPerine for enhanced bioavailability

Cons:

• Pricier than single-ingredient supplements

• Only available through select online stores

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2. Best Single-Ingredient Option: PartiQlar Pure Resveratrol

Key Details:

• Ingredients: 500 mg trans-resveratrol (from Japanese knotweed, 98%+ purity)

• Price: Around $31.44 for 60 capsules

• Ideal for: Those who prefer a simple, high-purity resveratrol supplement

PartiQlar Pure Resveratrol is made for minimalists who want a pure, single-ingredient formula. 

Each capsule contains 500 mg of highly purified trans-resveratrol, the active form your body can easily use. It’s sourced from Japanese knotweed and verified through third-party testing to guarantee potency and purity.

With no added fillers or unnecessary additives, PartiQlar focuses on delivering a clean, consistent dose that supports antioxidant defense and heart health. 

It’s ideal for long-term users who want a straightforward supplement at a fair price.

Pros:

• High purity (>98%) trans-resveratrol

• Simple and filler-free formula

• Third-party tested for quality assurance

• Good value for everyday use

Cons:

• No added absorption enhancer like BioPerine

• May not suit those looking for multi-ingredient blends

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3. Purest Trans-Resveratrol Extract: Decode Age Resveratrol Supplement

Key Details:

• Ingredients: 99% pure trans-resveratrol (from Japanese knotweed extract)

• Price: Typically around $40–$45 for a 30-day supply

• Ideal for: Those prioritizing purity and clean formulations

Decode Age Resveratrol Supplement stands out for its impressive 99% purity level. Extracted from Japanese knotweed, it delivers a clean, potent source of trans-resveratrol with no unnecessary additives or binders. 

The formula is designed for maximum absorption and purity, making it a good fit for people focused on quality and consistency.

This supplement supports heart and brain health while combating oxidative stress linked to aging. Decode Age’s reputation for scientific rigor and lab transparency gives this product strong credibility among longevity enthusiasts.

Pros:

• Exceptionally high purity (99%)

• Derived from trusted Japanese knotweed extract

• Free from additives, fillers, or binders

• Backed by lab testing for potency

Cons:

• Not widely available outside Decode Age’s official site

• Lacks absorption-enhancing ingredients

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4. Best High-Dose Resveratrol: ProHealth Longevity Trans-Resveratrol Plus

Key Details:

• Ingredients: 1000 mg trans-resveratrol, quercetin, red wine extract, green tea extract, BioPerine

• Price: Around $31.08 for 60 capsules

• Ideal for: Users seeking maximum strength and antioxidant synergy

ProHealth Longevity’s Trans-Resveratrol Plus is one of the strongest on the market, offering a full gram (1000 mg) of 99.5% pure trans-resveratrol per serving. 

It doesn’t stop there; it also includes antioxidant allies like quercetin, green tea extract, and BioPerine to improve absorption.

This makes it ideal for people who want a comprehensive antioxidant supplement for heart health, metabolic balance, and overall vitality. 

With third-party testing and over 30 years in the supplement industry, ProHealth brings both potency and trust.

Pros:

• High 1000 mg dose per serving

• Includes synergistic antioxidants for added support

• Contains BioPerine for better nutrient uptake

• Trusted longevity brand with third-party testing

Cons:

• Strong dose may not be necessary for beginners

• Contains multiple active compounds (not ideal for purists)

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5. Best for Absorption: Purovitalis Liposomal Resveratrol

Key Details:

• Ingredients: 250 mg trans-resveratrol (liposomal form)

• Price: €26.95 (about $29–$30) for 30 capsules

• Ideal for: Those who want high absorption and European-made quality

Purovitalis uses liposomal technology to make its resveratrol more bioavailable. This delivery system encases the active compound in lipid molecules that help it survive digestion and reach the bloodstream efficiently. 

Each capsule delivers 250 mg of trans-resveratrol sourced from Japanese knotweed, ensuring both quality and potency.

It’s vegan, non-GMO, and manufactured in the Netherlands to strict quality standards. 

While the dose may seem lower than some competitors, the liposomal form might make it significantly more effective per milligram.

Pros:

• Liposomal delivery improves absorption

• Clean, vegan, and non-GMO formula

• Made in the EU under strict quality control

• Ideal for people with sensitive digestion

Cons:

• Lower milligram amount per serving

• Slightly higher cost per capsule compared to standard forms

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6. Best Budget Pick: Nutricost Resveratrol 700 mg

Key Details:

• Ingredients: 700 mg resveratrol (from Japanese knotweed)

• Price: Around $21.95 for 120 capsules

• Ideal for: Budget-conscious users who want a simple, reliable resveratrol supplement

Nutricost Resveratrol is a straightforward formula that offers high dosage and solid quality at a fair price. Each serving delivers 700 mg of resveratrol sourced from Japanese knotweed, one of the most trusted plant sources. 

It’s made in a GMP-certified facility in the USA, ensuring safety and consistency with every batch. This supplement skips unnecessary additives and fancy delivery systems, focusing instead on giving you more resveratrol for your money. 

It’s a practical choice for anyone who wants long-term antioxidant support without overspending.

Pros:

• Excellent price-to-dose value

• Non-GMO and gluten-free

• Manufactured in a GMP-certified facility

• High dose for daily antioxidant support

Cons:

• No added absorption enhancers

• Plain capsule design, not optimized for bioavailability

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7. Best for Purity and Value: Toniiq Ultra High Purity Resveratrol

Key Details:

• Ingredients: 600 mg trans-resveratrol (standardized to 98% purity)

• Price: Around $38.22 for 180 capsules

• Ideal for: Users who want lab-tested, filler-free purity at a good value

Toniiq Ultra High Purity Resveratrol focuses on potency and clean formulation. Each capsule contains 600 mg of resveratrol standardized to 98% purity, sourced from Japanese knotweed. 

The brand is well known for its strict quality testing, ensuring every batch is free from heavy metals and contaminants.

This supplement is a favorite among health enthusiasts who value simple, no-nonsense ingredients. It offers great value for a high-purity formula, making it ideal for consistent daily use.

Pros:

• 98% standardized trans-resveratrol

• Third-party tested for purity and safety

• No fillers, preservatives, or artificial ingredients

• Great long-term value

Cons:

• No absorption enhancer like BioPerine

• Plain formulation without additional antioxidants

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8. Best Liposomal Capsule: Renue By Science LIPO Trans-Resveratrol

Key Details:

• Ingredients: 125 mg trans-resveratrol (liposomal form)

• Price: Around $49.95 for 60 capsules

• Ideal for: Those seeking a bioavailable, scientifically advanced formula

Renue By Science is known for its cutting-edge delivery technology, and their LIPO Trans-Resveratrol is a great example. 

Each capsule contains 125 mg of liposomal resveratrol, designed to improve absorption and ensure more of the active compound reaches your cells.

Although the dosage per capsule is modest, the liposomal form is often far more effective than higher-dose traditional powders. 

This makes it a smart choice for users who prioritize efficiency, purity, and scientifically backed delivery systems.

Pros:

• Liposomal technology enhances bioavailability

• Manufactured under pharmaceutical-grade standards

• Vegan, non-GMO, and filler-free

• Gentle on digestion

Cons:

• Higher cost per milligram

• Smaller serving size than standard capsules

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9. Best for Athletes and Recovery: Momentous Resveratrol

Key Details:

• Ingredients: 450 mg trans-resveratrol (from Japanese knotweed)

• Price: Around $48 for 60 capsules

• Ideal for: Athletes and active individuals focused on recovery and cardiovascular performance

Momentous Resveratrol is designed with performance in mind. It’s Informed-Sport certified, meaning every batch is tested for banned substances, a must for professional athletes. 

The 450 mg of trans-resveratrol helps combat oxidative stress from intense workouts, supporting muscle recovery and endurance.

With its clean formulation and third-party testing, Momentous is ideal for people who want the benefits of resveratrol without worrying about product purity or safety. 

The certification and brand reputation make it a top pick for the athletic community.

Pros:

• Certified by Informed-Sport for safety

• Great for athletic recovery and endurance

• Clean, vegan-friendly formula

• Reputable brand used by professionals

Cons:

• Higher price compared to basic resveratrol capsules

• Limited availability outside North America

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10. Best for Skin and Anti-Aging: Reserveage Resveratrol Beauty 500 mg

Key Details:

• Ingredients: 500 mg trans-resveratrol (from Japanese knotweed and red wine grapes), quercetin, and grape seed extract

• Price: Around $37.83 for 30 capsules

• Ideal for: Users focused on beauty, skin health, and cellular protection

Reserveage Resveratrol Beauty combines trans-resveratrol with quercetin and grape seed extract under its signature “Pro-Longevity Factors®” blend. 

Together, these antioxidants help combat oxidative stress that contributes to aging and skin dullness. 

It’s one of the few formulas that target both inner health and outward appearance, making it perfect for users who want anti-aging benefits alongside traditional heart and brain support. 

The ingredients are naturally sourced, and the product is non-GMO and gluten-free.

Pros:

• Focuses on both skin and longevity benefits

• Contains synergistic antioxidants like quercetin

• Non-GMO and gluten-free

• Trusted, beauty-oriented brand

Cons:

• Smaller bottle size for the price

• Not ideal for those wanting a single-ingredient formula

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11. Best Whole-Food Formula: Garden of Life Raw Resveratrol

Key Details:

• Ingredients: 350 mg raw fermented trans-resveratrol, fruit and vegetable blend, 500 million CFU probiotics

• Price: Around $39.54 for 60 capsules

• Ideal for: People who prefer a natural, plant-based, whole-food supplement

Garden of Life Raw Resveratrol blends trans-resveratrol from Japanese knotweed with organic fruit and vegetable extracts. 

What makes it unique is the inclusion of live probiotics and enzymes that support gut health while improving nutrient absorption.

This whole-food approach makes it perfect for those who value clean, organic nutrition. The fermented resveratrol is gentle on the digestive system and supports healthy aging, heart health, and immune balance in a natural way.

Pros:

• Includes probiotics and digestive enzymes

• Certified organic, vegan, and non-GMO

• Whole-food, fermented formula

• Supports both heart and gut health

Cons:

• Mild flavor and aroma due to fermentation

• Slightly higher price compared to basic formulas

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NMN + RESVERATROL

Cellular NAD+ booster with ultra‑pure NMN and Resveratrol, at research‑backed doses.*

Shop NMN + RESVERATROL

Shop NMN + RESVERATROL

What is Resveratrol?

Resveratrol is a natural compound found in red grapes, dark chocolate, and Japanese knotweed that supports heart health, brain function, and healthy aging.

It’s made up of resveratrol molecules, which act as powerful antioxidants and anti-inflammatory agents that protect cells from damage caused by daily stress and a poor diet.

This compound works by activating sirtuins, the proteins responsible for cellular repair, balance, and energy regulation. However, oral resveratrol in its natural state has low bioavailability, meaning the body absorbs only a small portion of it.

That’s why most supplements use the trans form of resveratrol, which is considered the most active and effective type for improving absorption.

To make resveratrol treatment more effective, modern formulas include active components such as BioPerine or liposomal delivery systems that enhance uptake.

Supplements are also available in different doses, allowing users to choose based on their individual health goals and tolerance.

Who Can Benefit from Resveratrol Supplements?

Resveratrol supplementation can be helpful for anyone who wants to support long-term health, energy, and graceful aging. Since resveratrol works at the cellular level to reduce oxidative stress and inflammation, it benefits a wide range of people, especially those with busy lifestyles or age-related concerns.

Here are a few groups who may benefit most:

• Adults over 35: Natural resveratrol levels in the body decline with age, making supplementation useful for supporting longevity and heart health.

• People with cardiovascular concerns: Resveratrol may help improve circulation and support healthy cholesterol levels.

• Those managing blood sugar: Studies show resveratrol can improve insulin sensitivity and metabolic function.

• Active individuals and athletes: Its anti-inflammatory properties help with recovery and muscle repair.

• Anyone under chronic stress: Antioxidants like resveratrol protect against the cellular damage linked to daily stress and poor sleep.

Key Benefits of Taking Resveratrol Supplements

Resveratrol has been widely studied for its impressive health benefits, especially in supporting heart and brain health and promoting overall longevity. It influences several pathways in the body that protect against oxidative stress, improve cell survival, and slow the aging process. 

Disclaimer: The following benefits are based on current research. Individual results may vary, and resveratrol should not replace professional medical advice or prescribed treatment.

Here are some of the most recognized beneficial effects seen in studies:

• Heart Health and Circulation: Studies suggest resveratrol supports cardiovascular health by reducing inflammation, promoting better blood flow, and helping regulate blood clotting (2). It may also lower LDL cholesterol and protect against heart disease and other forms of cardiovascular disease (2).

• Brain and Cognitive Function: Research shows resveratrol’s antioxidant action may protect brain cells from damage, supporting cognitive performance and mental clarity (3). Some studies also point to potential protection against Alzheimer’s disease and age-related decline in cognitive function (4).

• Blood Sugar and Metabolism: Resveratrol may help improve insulin sensitivity and stabilize blood sugar levels, especially in people with metabolic issues (5). Supporting better glucose control helps maintain steady energy levels throughout the day.

• Joint and Inflammatory Support: Its anti-inflammatory properties can help reduce joint discomfort and stiffness, making movement easier for those with arthritis or chronic inflammation (6).

• Longevity and Cellular Protection: In animal research, resveratrol mimics caloric restriction, a well-known trigger for lifespan extension (7). It supports cell survival, DNA repair, and mitochondrial health, all of which may help the body extend lifespan and age more gracefully.

Are Resveratrol Supplements Safe?

Resveratrol supplements are generally considered safe when taken within recommended doses, usually between 250 mg and 1000 mg per day. Most research reports mild or no side effects in healthy adults.

However, as with any supplement, it’s best to start slowly and observe how your body responds. Some people may experience mild, temporary effects such as:

• Digestive upset or bloating

• Headache or fatigue (if taken on an empty stomach)

• Mild dizziness in higher doses

If you are on blood-thinning medication (like warfarin or aspirin), have low blood pressure, or are pregnant or breastfeeding, consult your healthcare provider before taking resveratrol.

When used properly, resveratrol is well-tolerated and may even enhance the benefits of a balanced diet and regular exercise. Many people safely take it long-term as part of a daily longevity or heart health routine.

Food and Beverages Rich in Resveratrol

You don’t have to rely only on supplements to get resveratrol. It’s naturally present in a variety of plant-based foods and drinks known for their antioxidant and heart-supporting properties.

Here are some of the best natural sources:

• Red grapes: Especially the skin, which is rich in raw fermented resveratrol, the same form often used in quality supplements.

• Red wine: A moderate amount may support heart health thanks to its polyphenols, including resveratrol molecules derived from grape fermentation.

• Peanuts: A simple and nutritious snack that contains trace amounts of resveratrol.

• Dark chocolate and cocoa: Offer beneficial flavonoids and a small boost of natural resveratrol.

• Blueberries and cranberries: Packed with antioxidants and plant compounds that support healthy aging.

• Japanese knotweed: The main source of raw fermented Japanese knotweed extract, used to produce most supplement-grade resveratrol.

While these foods provide natural resveratrol, you’d need to consume large amounts daily to match the amount found in one capsule of a concentrated supplement. That’s why many people choose resveratrol supplements for more consistent and measurable benefits.

How to Choose the Best Resveratrol Supplement for You

Finding the right resveratrol supplement depends on your goals, budget, and how well your body absorbs it. Look for products that combine purity, transparency, and proven bioavailability.

Choose Trans-Resveratrol, Not Cis-Resveratrol

Trans-resveratrol is the active form your body recognizes and uses efficiently. Supplements that specify “trans-resveratrol” on the label offer better antioxidant and anti-aging potential than those using mixed or unspecified forms.

Check for Purity and Third-Party Testing

Aim for supplements with at least 98–99% purity and certifications from independent labs. This ensures you’re getting genuine, uncontaminated resveratrol free from heavy metals or additives.

Look for Enhanced Absorption

Resveratrol can be difficult to absorb in the gut. Look for formulas that include BioPerine (black pepper extract), micronized particles, or liposomal delivery systems. These methods improve bioavailability and make each dose more effective.

Choose the Right Dosage for Your Needs

For general wellness, 250–500 mg per day is enough. If you’re aiming for more targeted effects like cardiovascular or longevity support, doses up to 1000 mg are often used in studies. Always start low and increase gradually.

Consider Additional Supportive Ingredients

Some supplements combine resveratrol with NMN, quercetin, or green tea extract to enhance results. These compounds work synergistically, supporting metabolism, energy, and antioxidant defense.

Read more: Fisetin vs Quercetin: Which One is Right for You?

Final Words

Resveratrol continues to be one of the most fascinating supplements for promoting heart health, longevity, and energy production. From pure single-ingredient capsules to advanced liposomal blends, there’s something for every goal and budget. 

The key is choosing a supplement that’s high in trans-resveratrol, clinically dosed, and third-party tested so you know you’re getting the real thing.

If you’re looking for a resveratrol supplement that does more than just provide antioxidants, Omre NMN + Resveratrol is the clear choice. 

With equal parts NMN and resveratrol, plus BioPerine for better absorption, it supports your body’s natural energy, cellular repair, and long-term vitality, all in one daily capsule.

Shop Omre NMN + Resveratrol now and experience what smarter longevity feels like.

FAQs

What’s the best time to take resveratrol?

Most experts suggest taking resveratrol in the morning with food that contains healthy fats to help absorption. If you’re pairing it with NMN, both can be taken together at the same time for cellular energy support.

Is resveratrol safe to take daily?

Yes, resveratrol is generally well tolerated in doses of 250–1000 mg per day. However, people taking blood thinners or other medications should consult a healthcare provider before starting any supplement.

Can I take resveratrol with NMN or NAD+ boosters?

Yes. In fact, many longevity researchers recommend combining them since resveratrol helps activate sirtuins while NMN supports NAD+ production, both key for cellular repair and healthy aging.

How long does resveratrol take to work?

Most people start noticing subtle benefits in energy, skin tone, or focus within 4 to 8 weeks of consistent use. Deeper effects, like improved cardiovascular function, may take a few months of daily supplementation.